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Adatanserin

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Identification
Molecular formula
C25H32N2O2
CAS number
183266-36-2
IUPAC name
1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone
State
State

At room temperature, Adatanserin is a solid.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
396.56g/mol
Molar mass
396.5560g/mol
Density
1.1860g/cm3
Appearence

Adatanserin typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone

The solubility of 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone is an interesting aspect to consider, especially due to its complex structure.

Generally, the solubility of organic compounds can be influenced by several factors, including:

  • Polarity: Compounds that are polar tend to dissolve well in polar solvents, while non-polar compounds prefer non-polar solvents.
  • Molecular size: Larger molecules may have decreased solubility due to steric hindrance, which can affect solvation.
  • Functional groups: The presence of functional groups can enhance or reduce solubility in aqueous or organic solvents.

For 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone, its solubility prospects may include:

  • Potential solubility in organic solvents such as ethanol and DMSO, due to the lipophilic nature of the adamantyl and the aromatic ring.
  • Limited solubility in water, owing to the bulky adamantyl group which may reduce interactions with water molecules.

As quoted in many chemical studies, "The solubility of a compound is often a critical factor in its biological activity and application." Thus, understanding the solubility of this compound is essential for its utilization in pharmaceuticals and other fields. Further experimental studies are recommended to accurately profile its solubility characteristics.

Interesting facts

Interesting Facts about 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone

This compound, known for its unique structure and potential applications, is a fascinating area of study in medicinal chemistry. It incorporates a variety of functional groups and structural motifs that are significant for its biological activity.

Structural Significance

  • Adamantyl Group: The presence of the adamantyl moiety, a cage-like structure, contributes to the compound's rigidity and potentially enhances its binding affinity to biological targets.
  • Piperazine Ring: The inclusion of a piperazine ring is common in pharmaceuticals, often improving receptor interaction and solubility.
  • 2-Methoxyphenyl Substituent: This aromatic component may play a role in the compound's hydrophobic interactions which can be crucial for its pharmacological effects.

Biological Implications

The compound's design may be tailored for specific interactions within biological systems, suggesting possible therapeutic effects. Research has indicated such compounds could hold promise in:

  • Affecting neurotransmitter systems, particularly those related to mood and anxiety.
  • Potential anti-depressant or anxiolytic effects, stemming from the piperazine structure.
  • Modulating pathways involved in various neurochemical processes.

Research Perspectives

As scientists continue to explore novel compounds, those like 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone could pave the way for new treatments. Ongoing studies might delve into:

  • Structure-activity relationship (SAR) analyses to optimize therapeutic efficacy.
  • In vivo and in vitro tests to better understand its pharmacokinetics and dynamics.
  • Combining this compound with other agents to enhance its effects.

In summary, the exploration of this compound represents a thrilling intersection of synthetic organic chemistry and pharmacology. Its intricate design not only challenges chemists but also opens doors to significant advancements in drug development.

Synonyms
AKOS034413418
Z50118361