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Adapromine Hydrochloride

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Identification
Molecular formula
C21H29ClN2O2
CAS number
5978-38-3
IUPAC name
1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone;hydrochloride
State
State

At room temperature, Adapromine Hydrochloride is usually found in a solid state. It is stable under normal conditions and is used primarily in pharmaceutical syntheses.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
607.80
Boiling point (Kelvin)
880.95
General information
Molecular weight
412.98g/mol
Molar mass
412.9830g/mol
Density
1.1844g/cm3
Appearence

Adapromine Hydrochloride typically appears as a white to off-white crystalline powder. It is often supplied in a solid form suitable for pharmaceutical applications and research.

Comment on solubility

Solubility of 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone; hydrochloride

The solubility of the compound 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone; hydrochloride can be quite complex due to its unique structure. Understanding its solubility is crucial for various applications and formulations. Here are some key points to consider:

  • Solvent Polarity: The solubility of this compound may vary significantly depending on the nature of the solvent. Generally, it is expected to have better solubility in polar solvents compared to non-polar ones.
  • Hydrochloride Form: As a hydrochloride salt, this compound typically exhibits increased solubility in aqueous solutions compared to its free base form. This is often because the charged species can interact more favorably with water molecules.
  • Temperature Effects: Temperature can also influence solubility. In many cases, increasing the temperature enhances solubility due to increased molecular motion.

In summary, the solubility of 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone hydrochloride is largely determined by solvent choice, chemical form, and temperature. Thorough experimentation may be needed to define specific solubility characteristics more precisely.

Interesting facts

Interesting Facts about 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone;hydrochloride

This compound, often referred to as an adamantyl derivative, showcases some fascinating characteristics and applications within the realm of medicinal chemistry. Here are some notable aspects:

  • Chemical Structure: The structure of this compound includes an adamantyl moiety, which is known for its unique cage-like structure. This feature often enhances the compound's stability and bioavailability.
  • Potential Therapeutic Uses: Compounds containing piperazine rings, like this one, have been investigated for their potential as antidepressants and anxiolytics. The piperazine component in this molecule is an attractive scaffold in drug design due to its versatility.
  • Interactions: The 2-methoxyphenyl group contributes to the lipophilicity of the compound, which may affect its interaction with biological membranes as well as its binding affinity to various receptors in the brain.
  • Research Implications: The study of this compound can provide insights into structure-activity relationships (SAR) in drug design, enabling chemists to modify the existing structure to enhance efficacy and reduce side effects.
  • Mechanism Exploration: This compound can serve as a lead for investigating the mechanisms of action of similar compounds in the central nervous system, shedding light on how modifications can lead to differential pharmacological effects.

As a compound of interest, 1-(1-adamantyl)-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone; hydrochloride represents a bridge between fundamental chemistry and practical pharmaceutical applications. Its unique components and potential therapeutic effects make it a notable subject for students and researchers alike.

Synonyms
KETONE, 1-ADAMANTYL (4-(o-METHOXYPHENYL)-1-PIPERAZINYL)METHYL, MONOHYDROCHLORIDE
1-Adamantyl (4-(o-methoxyphenyl)-1-piperazinyl)methyl ketone monohydrochloride
23479-49-4
DTXSID90178040
RefChem:350383
DTXCID20100531