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1-(1-Ethylindol-3-yl)-2-(methylamino)ethanol

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Identification
Molecular formula
C14H20N2O
CAS number
113-92-8
IUPAC name
1-(1-ethylindol-3-yl)-2-(methylamino)ethanol
State
State

The compound is typically found as a solid at room temperature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
218.29g/mol
Molar mass
218.2940g/mol
Density
1.1870g/cm3
Appearence

1-(1-Ethylindol-3-yl)-2-(methylamino)ethanol appears as a crystalline solid with a white to off-white coloration. It is often found in a refined form with no significant odor.

Comment on solubility

Solubility of 1-(1-ethylindol-3-yl)-2-(methylamino)ethanol

When considering the solubility of the compound 1-(1-ethylindol-3-yl)-2-(methylamino)ethanol, several factors come into play:

  • The presence of multiple functional groups, particularly the amino and alcohol groups, often enhances solubility in polar solvents like water.
  • However, the indole structure, which is typically hydrophobic, may limit solubility in aqueous environments.
  • Solubility may also be significantly influenced by the pH of the solution, as the protonation state of the amino group can change with the pH, affecting its interaction with water.

In general, one might find that:

  1. In neutral pH conditions, the compound may exhibit moderate solubility.
  2. In acidic conditions, the amino group is protonated, likely increasing solubility.
  3. In basic conditions, the compound may become less soluble due to potential precipitation of less polar forms.

In conclusion, while the overall solubility of 1-(1-ethylindol-3-yl)-2-(methylamino)ethanol is influenced by a combination of functional groups and environmental conditions, it remains imperative to conduct empirical testing to determine its precise solubility characteristics in various solvents.

Interesting facts

Interesting Facts About 1-(1-ethylindol-3-yl)-2-(methylamino)ethanol

1-(1-ethylindol-3-yl)-2-(methylamino)ethanol is a fascinating compound often studied in the fields of medicinal chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structural Significance: The presence of the indole structure lends this compound unique properties, as indoles are known for their versatility in biological systems.
  • Biological Activities: Compounds with similar structures have shown various biological activities, including potential antidepressant and anxiolytic effects. This makes it an interesting candidate for further research in mental health therapies.
  • Research Potential: The methylamino group in this compound may contribute to its polarity, which affects its interaction with biological targets, thereby warranting studies on its pharmacokinetics and pharmacodynamics.
  • Analytical Importance: This compound can serve as a model in analytical chemistry, providing insights into how modifications in molecular structure can influence reactivity and binding affinity to receptors.

As noted in the literature, *"the indole alkaloids possess significant therapeutic potential, making them targets of interest in drug development."* This compound, therefore, represents not only a piece of molecular architecture but also a hope for finding novel therapeutic agents.

Ongoing studies related to such compounds can lead to advancements in understanding complex biological processes, ultimately benefiting medicinal chemistry and pharmacology.

Synonyms
1-Ethyl-alpha-((methylamino)methyl)indole-3-methanol
5135-81-9
NSC 19971
BRN 0397330
NSC19971
INDOLE-3-METHANOL, 1-ETHYL-alpha-((METHYLAMINO)METHYL)-
NSC-19971