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1-(1-Methoxyethyl)indole

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Identification
Molecular formula
C11H13NO
CAS number
16989-85-0
IUPAC name
1-(1-methoxyethyl)indole
State
State

At room temperature, 1-(1-Methoxyethyl)indole is a liquid. It is stable under normal conditions but should be stored in a cool, dry place to maintain its stability and prevent any alteration.

Melting point (Celsius)
-13.00
Melting point (Kelvin)
260.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
189.24g/mol
Molar mass
189.2430g/mol
Density
1.0330g/cm3
Appearence

1-(1-Methoxyethyl)indole is typically a colorless to pale yellow liquid. It may have a characteristic odor, which is common for many indole derivatives.

Comment on solubility

Solubility of 1-(1-methoxyethyl)indole

The solubility of 1-(1-methoxyethyl)indole in various solvents can provide valuable insights into its chemical behavior and potential applications. Understanding its solubility is crucial for pharmacological studies and chemical synthesis.

The solubility profile of 1-(1-methoxyethyl)indole can be summarized as follows:

  • Solvent Polarity: Generally, 1-(1-methoxyethyl)indole is expected to be more soluble in polar solvents due to the presence of the methoxy group. This group enhances solvation through dipole-dipole interactions.
  • Water Solubility: This compound may exhibit limited solubility in water, as indole derivatives often struggle with solubility in polar solvents unless modified by additional functional groups.
  • Organic Solvents: It is likely to be soluble in organic solvents such as ethanol, methanol, and acetone, which can accommodate its hydrophobic aromatic structure.

As noted in various studies, the interaction of the methoxy group with the indole core significantly influences solubility. A pertinent observation is that the solubility can vary widely depending on factors such as temperature and solvent composition. Therefore, when working with 1-(1-methoxyethyl)indole, the choice of solvent is critical for achieving desired concentrations and reactions.

Interesting facts

Exploring 1-(1-Methoxyethyl)indole

1-(1-methoxyethyl)indole is a fascinating organic compound that belongs to the indole family, which is known for its rich diversity in natural products and bioactive compounds. This particular derivative displays some intriguing characteristics and potential applications:

  • Structural Interest: The methoxyethyl group attached to the indole structure contributes to its unique reactivity, making it an important scaffold for further chemical modifications.
  • Biological Relevance: Many indole derivatives exhibit significant biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. This compound may also share similar potential, warranting further investigation.
  • Research Applications: The compound plays a crucial role in synthetic organic chemistry, serving as a precursor for the synthesis of more complex molecules. Its unique structure allows chemists to explore various synthetic routes and transformations.
  • Interdisciplinary Importance: Beyond chemistry, 1-(1-methoxyethyl)indole has applications in fields such as pharmacology and materials science, highlighting the compound's versatility.

As students and researchers continue to uncover the properties of 1-(1-methoxyethyl)indole, they may discover innovative uses that continue to bridge the gap between chemistry and various scientific disciplines. In the words of famous chemist Linus Pauling:

"The best way to have a good idea is to have a lot of ideas."

With the study of compounds like 1-(1-methoxyethyl)indole, the possibilities are indeed endless!

Synonyms
1H-Indole, 1-(1-methoxyethyl)-
1-(alpha-Methoxyethyl)indole
22942-81-0
1-(1-methoxyethyl)indole
1-[1-methoxyethyl]indole
BRN 4988516
1-(1-Methoxyethyl)-1H-indole
INDOLE, 1-(1-METHOXYETHYL)-
RefChem:1058152
indole-3-methyl-ethanolate
SCHEMBL2945924
SCHEMBL6425937
DTXSID20945626
KZLMZUCDWYXVJZ-UHFFFAOYSA-N