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Pergolide

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Identification
Molecular formula
C19H26N2O
CAS number
66104-22-1
IUPAC name
1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea
State
State
The compound is typically a solid at room temperature, forming a stable structure under standard conditions.
Melting point (Celsius)
178.50
Melting point (Kelvin)
451.65
Boiling point (Celsius)
580.60
Boiling point (Kelvin)
853.75
General information
Molecular weight
314.42g/mol
Molar mass
314.4170g/mol
Density
1.1800g/cm3
Appearence

The compound appears as a white to off-white solid that may be crystalline in nature. Its powdered form is often used in laboratory settings and chemical analysis.

Comment on solubility

Solubility of 1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea

The solubility of 1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea is a notable topic of interest in the realm of chemical compounds. This compound exhibits unique solubility characteristics influenced by its structural features and functional groups.

Key points regarding the solubility of this compound include:

  • Solvent Dependence: The solubility can vary significantly based on the solvent used. For instance, it tends to be more soluble in organic solvents than in water.
  • Hydrophobic Interactions: The presence of the diphenyl group in its structure contributes to its hydrophobic nature, often resulting in poor solubility in polar solvents such as water.
  • Temperature Influence: Solubility is also affected by temperature, generally increasing as the temperature rises.
  • pH Sensitivity: Changes in pH can impact ionization, leading to variations in solubility, especially in aqueous environments.

As a result, it is essential to consider these factors when assessing the solubility of 1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea for applications in pharmaceutical or chemical research. This underscores the complexity and intricacies involved in understanding solubility and its implications in practical scenarios.

Interesting facts

Interesting Facts about 1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea

1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea is a fascinating compound with a rich background in both structure and potential applications. Here are some engaging insights:

  • Pharmaceutical Developments: This compound is notable for its role in medicinal chemistry, where it serves as a scaffold for the design of various therapeutic agents. The unique structure allows for modifications that can enhance biological activity.
  • Mechanism Insights: Research has shown that the presence of the pyrrolidine ring can influence the compound's interaction with biological targets, potentially affecting its efficacy and selectivity.
  • Solubility Influences: The diphenyl moiety in the structure contributes significantly to the compound's lipophilicity, which can affect its absorption and distribution in biological systems.

The synthetic pathways for creating this compound typically involve:

  1. Formation of the urea linkage.
  2. Introduction of the pyrrolidine group, which can be achieved through various alkylation techniques.
  3. Final adjustments to optimize the diphenyl substituents for desired pharmacological properties.

In summary, 1-(1-methylpyrrolidin-3-yl)-1,3-diphenyl-urea exemplifies the complexities of organic chemistry and the intricate designs found in nature, opening doors to potential innovations in pharmaceuticals and beyond.

Synonyms
1,3-Diphenyl-1-(1-methyl-3-pyrrolidinyl)urea
19996-88-4
1-(1-methylpyrrolidin-3-yl)-1,3-diphenylurea
BRN 0427900
N-(1-Methyl-3-pyrrolidinyl)carbanilide
CARBANILIDE, N-(1-METHYL-3-PYRROLIDINYL)-
DTXSID00941969
N-(1-Methylpyrrolidin-3-yl)-N,N'-diphenylcarbamimidic acid