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Homoquinoline

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Identification
Molecular formula
C16H19NO
CAS number
24467-00-5
IUPAC name
1-(1-piperidylmethyl)naphthalen-2-ol
State
State

At room temperature, 1-(1-piperidylmethyl)naphthalen-2-ol can be found in a solid state. The exact form (solid or liquid) can vary based on purity and experimental conditions.

Melting point (Celsius)
45.00
Melting point (Kelvin)
318.15
Boiling point (Celsius)
87.00
Boiling point (Kelvin)
360.15
General information
Molecular weight
241.33g/mol
Molar mass
241.3310g/mol
Density
1.2060g/cm3
Appearence

The compound is typically a colorless to pale yellow liquid or solid, depending on experimental conditions. Being aromatic, it may emit a characteristic odor associated with naphthalenes.

Comment on solubility

Solubility of 1-(1-piperidylmethyl)naphthalen-2-ol

The solubility of 1-(1-piperidylmethyl)naphthalen-2-ol can be influenced by several factors, making it an interesting compound to consider. Here are some key points regarding its solubility:

  • Polar and Nonpolar Properties: This compound features both polar and nonpolar regions, which could allow for varying solubility in different solvents.
  • Solvent Compatibility: It is likely to be soluble in polar solvents such as water or alcohols, given the presence of the hydroxyl group (-OH), while showing limited solubility in nonpolar solvents.
  • Hydrogen Bonding: The presence of the hydroxyl group can facilitate hydrogen bonding interactions with water molecules, enhancing its solubility in aqueous solutions.
  • pH Dependency: The solubility may also be influenced by pH levels, as changes in pH can affect the protonation state of the piperidine nitrogen.

In conclusion, while specific solubility values may vary, understanding how 1-(1-piperidylmethyl)naphthalen-2-ol interacts with different solvents provides insights into its potential applications in various chemical and pharmaceutical contexts. As always, empirical data should be consulted for precise solubility information.

Interesting facts

Interesting Facts About 1-(1-Piperidylmethyl)naphthalen-2-ol

1-(1-Piperidylmethyl)naphthalen-2-ol is a fascinating compound that has garnered interest in various fields of research. Here are some intriguing aspects of this compound:

  • Unique Structure: The compound features a naphthalene ring system fused with a piperidine substituent, which contributes to its unique biochemical properties.
  • Applications in Medicine: This compound has potential therapeutic applications, particularly in the fields of neuroscience and pharmacology, where it could play a role in the development of new medications targeting the central nervous system.
  • Research Interests: Chemists and pharmacologists are keen on studying its structure-activity relationship, trying to uncover how alterations to its structure affect its biological activity.
  • Mechanism of Action: Preliminary studies suggest that this compound may interact with specific receptors in the brain, affecting neurotransmitter systems and potentially influencing mood and cognition.
  • Insights into Naphthalene Chemistry: The naphthalene component opens up discussions about polycyclic aromatic hydrocarbons and their reactivity, providing insights into how such compounds can be synthesized and modified for various applications.
  • Safety and Handling: As with many organic compounds, it is essential to understand the safety guidelines and proper handling techniques when working with 1-(1-piperidylmethyl)naphthalen-2-ol in the laboratory.

In summary, 1-(1-piperidylmethyl)naphthalen-2-ol is a compound that holds significant promise in medicinal chemistry, offering a window into the interplay between structure and biological function. As research continues, we can expect to uncover more about this intriguing compound and its potential impacts.

Synonyms
5342-95-0
1-(piperidin-1-ylmethyl)naphthalen-2-ol
1-(piperidin-1-ylmethyl)-2-naphthol
1-(Piperidinomethyl)-2-naphthol
1-((piperidin-1-yl)methyl)naphthalen-2-ol
1-Piperidin-1-ylmethyl-naphthalen-2-ol
MLS002637703
1-[(piperidin-1-yl)methyl]naphthalen-2-ol
2-Naphthalenol, 1-(1-piperidinylmethyl)-
SMR001354233
alpha-Piperidinomethyl-beta-naphthol
Maybridge1_000036
Ro 3-0514
BRN 0185859
AI3-23150
MFCD00021615
2-NAPHTHOL, 1-(PIPERIDINOMETHYL)-
piperidinomethyl-2-naphthol
MixCom1_000058
Oprea1_565081
Oprea1_733906
5-20-02-00241 (Beilstein Handbook Reference)
cid_21436
1-piperidinylmethyl-2-naphthol
CHEMBL2005694
SCHEMBL13700903
BDBM91378
DTXSID50201585
NSC3684
2-Naphthol, 1-piperidino-methyl-
HMS3085I21
1-Piperidin-1-ylmethyl-2-naphthol
NSC 3684
NSC-3684
1-(1-piperidinylmethyl)-2-naphthol
CCG-46214
1-(1-piperidylmethyl)naphthalen-2-ol
AKOS000605809
1-(1-piperidinylmethyl)-2-naphthalenol
TS-00724
DB-032424
1-(piperidin-1-yl-methyl)-naphthalen-2-ol
CS-0307846
EN300-08750
L10053
MLS-0440404.0001
SR-01000635926-1
Z44087463