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1-Piperidinylpropionone

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Identification
Molecular formula
C8H15NO
CAS number
771-98-2
IUPAC name
1-(1-piperidyl)propan-1-one
State
State

At room temperature, 1-Piperidinylpropionone is typically a liquid.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
141.21g/mol
Molar mass
141.2110g/mol
Density
1.0075g/cm3
Appearence

1-Piperidinylpropionone appears as a colorless to pale yellow liquid. It is often described as having a pungent odor.

Comment on solubility

Solubility of 1-(1-piperidyl)propan-1-one

1-(1-piperidyl)propan-1-one, a compound containing a piperidine ring, exhibits unique solubility characteristics that are influenced by its functional groups.

Key Points on Solubility:

  • Polarity: The presence of both a ketone group and a piperidine moiety contributes to moderate polarity, affecting solubility in various solvents.
  • Solvent Compatibility: This compound is generally soluble in organic solvents such as ethanol, acetone, and dichloromethane due to its ability to engage in dipole-dipole interactions and hydrogen bonding.
  • Aqueous Solubility: While 1-(1-piperidyl)propan-1-one may have limited solubility in water, it can exhibit some degree of solubility owing to its polar functional groups.
  • Temperature Influence: Solubility can be affected by temperature; as the temperature increases, solubility in organic solvents typically increases.

In conclusion, understanding the solubility of 1-(1-piperidyl)propan-1-one is crucial for its applications in synthesis and pharmaceuticals. As one expert noted, "Solubility is a key factor in determining the bioavailability and reactivity of compounds." Exploring its solubility profile provides insight into the compound's behavior in various environments.

Interesting facts

Exploring 1-(1-Piperidyl)propan-1-one

1-(1-Piperidyl)propan-1-one, also known as 1-Piperidyl propan-1-one, is a fascinating compound predominantly recognized in the realm of organic chemistry. It belongs to the amino ketone class and is often utilized in various chemical synthesis processes.

Interesting Facts:

  • Usage in Synthesis: This compound plays a pivotal role as a precursor in the synthesis of various pharmaceuticals and agrochemicals.
  • Structural Characteristics: The presence of the piperidine ring contributes to its chemical reactivity, making it a valuable building block in creating more complex organic molecules.
  • Research Applications: Researchers are particularly interested in 1-(1-piperidyl)propan-1-one for its potential biological activities. Studies suggest it may exhibit properties useful in medicinal chemistry.
  • Derivative Formation: This compound can serve as a core structure for synthesizing derivatives, which are often tailored for specific interactions in biological systems.
  • Safety Precautions: While working with this compound, it is important to follow appropriate safety measures due to potential health risks associated with chemical exposure. Always consult safety data sheets (SDS) when handling chemicals.

As you dive deeper into the world of organic compounds, 1-(1-piperidyl)propan-1-one exemplifies the intricate relationships between structure and function. Its versatility in synthesis underlines the importance of understanding chemical reactivity and the potential for applications in medicine and beyond.

Synonyms
1-Propionylpiperidine
14045-28-4
1-piperidin-1-ylpropan-1-one
N,N-Pentamethylenepropionamide
1-Propanoylpiperidine
N-Pentamethylenepropionamide
N-Propionylpiperidin
N-Propionylpiperidin [German]
BRN 0111498
Piperidine, 1-(1-oxopropyl)-
AI3-36633
PIPERIDINE, 1-PROPIONYL
1-(piperidin-1-yl)propan-1-one
Piperidine, 1-(1-oxopropyl)- (9CI)
(1-oxo-propyl)-piperidine
5-20-02-00443 (Beilstein Handbook Reference)
SCHEMBL556384
SCHEMBL765761
SCHEMBL855713
SCHEMBL950791
SCHEMBL2644912
SCHEMBL7247970
SCHEMBL10644138
DTXSID20161400
MTJVUMGKHCIMJL-UHFFFAOYSA-N
AKOS008927833