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Olanzapine

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Identification
Molecular formula
C17H20N4OS
CAS number
132539-06-1
IUPAC name
1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one
State
State

At room temperature, Olanzapine is typically in a solid state. This medication is often provided in tablet form for oral administration.

Melting point (Celsius)
195.50
Melting point (Kelvin)
468.70
Boiling point (Celsius)
488.60
Boiling point (Kelvin)
761.80
General information
Molecular weight
312.44g/mol
Molar mass
312.4370g/mol
Density
1.2903g/cm3
Appearence

Olanzapine typically appears as a white to slightly yellow crystalline powder. It is often used in a finely powdered form for pharmaceutical applications.

Comment on solubility

Solubility of 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one

Understanding the solubility of 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one is crucial, given its complex structure which influences its interaction with solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of both the piperazine moiety and the phenothiazine structure suggests potential polarity, impacting solubility in various solvents.
  • Solvent Types: This compound is likely to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), rather than in polar protic solvents like water.
  • Hydrogen Bonding: The ability of certain functional groups to form hydrogen bonds can enhance solubility in polar solvents; however, the bulkiness of the compound may hinder this to some extent.
  • Temperature Dependency: As with many compounds, solubility may increase with temperature, allowing for a better understanding of its behavior in different environments.

In summary, the solubility of 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one is a multifaceted aspect, significantly influenced by its structural characteristics and the type of solvent used. While it shows potential for reasonable solubility in non-polar and moderately polar organic solvents, its overall behavior may require empirical testing to assess the complete scope of its solubility properties.

Interesting facts

Interesting Facts about 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one

This complex organic compound is a notable member of the phenothiazine family, which is characterized by a tricyclic structure. Here are some intriguing aspects worth noting:

  • Diverse Applications: Compounds within the phenothiazine class, including this one, have been extensively studied for their pharmacological properties. They often exhibit activity as antipsychotics and have been used in the treatment of various psychiatric disorders.
  • Chemical Structure: The presence of a methylpiperazine moiety in the structure suggests potential for enhanced efficacy in medicinal chemistry, allowing for improved binding to specific biological targets.
  • Research Potential: Due to its intricate chemical framework, this compound offers vast opportunities for research into new class pharmaceuticals, especially in the fields of neurochemistry and drug development.
  • Connecting Various Fields: The synthesis of this compound can serve as a bridge between organic chemistry and medicinal chemistry, demonstrating how traditional organic synthesis techniques can be applied in drug discovery and development.

The research surrounding such compounds can lead to a better understanding of significant health challenges, consequently improving therapeutic approaches. As one delves deeper into the 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one, it is essential to recognize its potential impact in the realms of science and medicine.

By studying compounds like this, scientists can pave the way toward innovative treatments and enhance the quality of life for individuals dealing with mental health issues.

Synonyms
BUTAPERAZINE
Butyrylperazine
653-03-2
Megalectil
Randolectil
Emerex
Repoise
Riker 595
Bayer 1362
Butaperazina
Tyrylen
Butyrylyperazine
Perazine, butyryl-
Butaperazinum
Perazine, (1-oxobutyl)-
Butaperazine [USAN:INN]
AHR 712
AHR-712
Butaperazinum [INN-Latin]
Butaperazina [INN-Spanish]
AHR-3000
HSDB 3297
EINECS 211-493-9
UNII-TXP4T9106S
RIKER-595
1-Butanone, 1-(10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)-
BAYER-1362
TXP4T9106S
Butaperazine (USAN)
BUTAPERAZINE [MI]
BUTAPERAZINE [INN]
BUTAPERAZINE [HSDB]
BUTAPERAZINE [USAN]
1-(10-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazin-2-yl)-1-butanone
1-Butanone, 1-(10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazin-2-yl)-
BUTAPERAZINE [WHO-DD]
DTXSID1022712
2-Butyryl-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine
3-n-Butyryl-10-(3'-N-methyl-piperazino-N'-propyl)phenothiazin
N-(gamma-(4'-Methyl-1'-piperazinyl)propyl)-3-butyrylphenothiazine
1-(10-(3-(4-Methyl-1-piperazinyl)-propyl)-10H-phenothiazin-2-yl)-1-butanone
1-Butanone, 1-[10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazin-2-yl]-
2-Butyryl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine
1-{10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazin-2-yl}butan-1-one
Butaperazinum (INN-Latin)
Butaperazina (INN-Spanish)
3-n-Butyryl-10-(3'-N-methyl-piperazino-N'-propyl)phenothiazine
1-(10-[3-(4-Methyl-1-piperazinyl)propyl]phenothiazin-2-yl)-1-butanone
1-{10-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazin-2-yl}-1-butanone
Emere
1-{10-[3-(4-Methyl-1-piperazinyl)propyl]phenothiazin-2-yl}-1-butanone
1-(10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazin-2-yl)butan-1-one
RIKER 59S
DTXCID702712
211-493-9
dvlbytmysmakhp-uhfffaoysa-n
Butaperazine Dihydrochloride
Butyrylperazine; Emerex; Megalectil
80463-18-9
1- 10-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazin-2-yl -1-butanone
1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one
SCHEMBL119995
CHEMBL1697826
CHEBI:135663
AKOS040745640
DB13213
NS00004549
D02642
EN300-19748930
Q5002359
1-(10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazin-2-yl)-1-butanone #