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Fluphenazine

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Identification
Molecular formula
C22H26N3OS
CAS number
69-23-8
IUPAC name
1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone
State
State

At room temperature, fluphenazine is in a solid state. It is normally processed or administered in liquid form, such as solutions for injection, or in solid tablets.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
366.50
Boiling point (Kelvin)
639.65
General information
Molecular weight
437.55g/mol
Molar mass
437.5540g/mol
Density
1.1920g/cm3
Appearence

Fluphenazine is typically found in the form of a white to slightly yellow crystalline powder. It may appear as slightly off-white when impurities are present, but the pure compound is nearly colorless.

Comment on solubility

Solubility of 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone

The solubility of the compound 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone can be influenced by various factors, particularly its complex molecular structure. Understanding its solubility characteristics is crucial for its applications in pharmacology and materials science. Here are some key points to consider:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents (e.g., water) while reducing solubility in non-polar solvents.
  • Temperature: Higher temperatures generally increase solubility, making it essential to assess the solubility behavior at different temperatures.
  • pH Levels: The ionization state of the molecule can significantly affect solubility; thus, it can vary in different pH environments.
  • Solvent Compatibility: The choice of solvent is crucial; it may exhibit higher solubility in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol rather than aqueous solutions.

In conclusion, the compound's solubility is a multifaceted property affected by its structural components and environmental conditions. As a result, it is essential to conduct specific solubility tests to obtain accurate and relevant data for practical use.

Interesting facts

Fascinating Insights on 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone

1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone, often referred to in the scientific community for its complex structure and potential therapeutic applications, is a notable compound in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound features a phenothiazine backbone, a well-known moiety in a variety of pharmaceutical agents, especially antipsychotics. The presence of the piperazine ring in its structure further enhances its binding properties to neurotransmitter receptors.
  • Pharmacological Potential: Research suggests that derivatives of phenothiazines exhibit diverse biological activities, including antipsychotic, antidepressant, and antiemetic properties. This makes the compound particularly interesting for further study in the field of neuropharmacology.
  • Drug Design: The incorporation of a piperazine moiety can improve the drug's efficacy and safety profile. The unique arrangement allows for selective interaction with specific receptors in the brain, which is a focus for developing next-generation pharmaceuticals.
  • Studying Interactions: As a complex organic molecule, this compound provides researchers with a rich avenue for exploring molecular interactions, stability, and reactivity in various conditions. It serves as an excellent candidate for computational modeling and synthesis in laboratories.

In summary, 1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone stands as an exemplary compound highlighting the interplay between structure and function in medicinal chemistry. Its multifaceted characteristics underscore the importance of exploring such compounds further for their potential applications in treating various neuropsychiatric disorders.

Synonyms
1053-74-3
KETONE, METHYL 10-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)PHENOTHIAZIN-2-YL
3-Acetyl-10-(3'N-methyl-piperazino-N'-propyl)phenothiazin
1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]ethanone
BRN 0766914
Methyl 10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazin-2-yl ketone
SCHEMBL141601
DTXSID40147064
1-(10-(3-(4-methylpiperazin-1-yl)propyl)-10h-phenothiazin-2-yl) ethanone