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Proflavine

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Identification
Molecular formula
C21H25N3O1S1
CAS number
92-62-6
IUPAC name
1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholino-ethanone
State
State

Proflavine is typically in a solid state at room temperature. It is often supplied as a powder for laboratory and research use, particularly in microbiological labs where its staining properties can be applied.

Melting point (Celsius)
267.00
Melting point (Kelvin)
540.15
Boiling point (Celsius)
560.00
Boiling point (Kelvin)
833.15
General information
Molecular weight
393.54g/mol
Molar mass
393.5360g/mol
Density
1.3000g/cm3
Appearence

Proflavine typically appears as a reddish-orange crystalline powder. It is known for its intense color and is often used as a biological stain due to its vibrant appearance under a microscope. Its crystalline structure allows it to form well-defined crystals.

Comment on solubility

Solubility of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholino-ethanone

The compound 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholino-ethanone, with the chemical formula C21H25N3O1S1, demonstrates intriguing solubility characteristics. As a phenothiazine derivative, its solubility profile can be influenced by both its hydrophobic and hydrophilic components. Here are some key points about its solubility:

  • Polar and Non-Polar Balance: The presence of a morpholino group and a dimethylamino group suggests the potential for good solubility in polar solvents such as water and alcohols, while the phenothiazine moiety contributes to its solubility in non-polar solvents.
  • Solvent Dependence: The solubility of this compound can be significantly different in varying solvents, emphasizing the need for specific solvent selection in applications or formulations.
  • pH Influence: The solubility may also be affected by pH, particularly due to the presence of basic amine groups that can protonate in acidic conditions, enhancing water solubility.

In summary, while this compound possesses characteristics that can enhance its solubility in diverse solvents, the definitive solubility profile may vary based on environmental conditions and specific interactions with the solvent used. Understanding these traits is essential for effective utilization in chemical synthesis and pharmaceutical formulations.

Interesting facts

Interesting Facts about 1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]-2-morpholino-ethanone

This compound, a member of the phenothiazine family, showcases a fascinating combination of structural complexity and potential applications. Here are some noteworthy aspects:

  • Pharmacological Potential: Phenothiazines are widely known for their use as antipsychotic agents and anxiolytics. This particular compound's unique structure could enhance its therapeutic efficacy, making it a candidate for further drug development.
  • Dimethylamino Group: The presence of a dimethylamino group contributes to the compound's lipophilicity, potentially affecting its bioavailability and mechanism of action.
  • Morpholine Ring: The morpholino component could play a crucial role in improving the solubility and stability of the compound in biological systems.
  • Research Insights: Scientists are particularly intrigued by how the phenothiazine core interacts with various biological targets. Structural modifications can lead to significant variations in pharmacological activities.

As you explore the mechanisms of action for compounds like this, keep in mind the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." Creativity in modification and synthesis can unlock new therapeutic pathways.

In summary, 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholino-ethanone is more than just a chemical formula; it represents a realm of possibilities in medicinal chemistry and pharmacology, paving the way for innovations that better human health.

Synonyms
13065-64-0
BRN 0582648
KETONE, 10-(3-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YL MORPHOLINOMETHYL-
DTXSID90156666
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(morpholinoacetyl)-
DTXCID3079157
1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholin-4-ylethanone
1-[10-(3-Dimethylaminopropyl)-10H-phenothiazin-2-yl]-2-morpholinoethanone