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Methylene Blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one
State
State

At room temperature, methylene blue is generally found in solid powder form. When hydrated, it can appear as small blue or green crystals.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8500g/mol
Density
1.1500g/cm3
Appearence

Methylene blue typically appears as a dark green crystalline powder. It is also available in a hydrated form that appears as a blue to green powder.

Comment on solubility

Solubility Insights for 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one

The solubility of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one can be quite complex due to its unique molecular structure, which features both hydrophobic and hydrophilic elements. Understanding its solubility is crucial for applications in pharmacology and material science.

Factors Influencing Solubility

  • Molecular Structure: The presence of a phenothiazine core combined with a long alkyl chain can enhance lipophilicity, making it more soluble in organic solvents.
  • Polarity: The dimethylamino group adds a polar character, which can influence solubility in polar solvents like water.
  • Temperature: Increased temperatures generally enhance solubility for many compounds, potentially aiding in dissolution in various solvents.

As a result, it is often observed that:

  1. 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one exhibits higher solubility in organic solvents.
  2. It may show limited solubility in aqueous solutions.
  3. The solubility can be modified through pH adjustments or the use of solubilizing agents.

In conclusion, while the solubility profile of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one is influenced by several factors, understanding its behavior in different solvent systems is essential for its effective application in various scientific fields.

Interesting facts

Interesting Facts about 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one

This intriguing compound belongs to the class of phenothiazines, which are known for their wide-ranging biological activities, particularly in the field of pharmacology. Here are some fascinating insights about its properties and uses:

  • Pharmacological Significance: Phenothiazines have a long-standing history in medicine, primarily as antipsychotic agents. They are commonly used to treat conditions such as schizophrenia and severe anxiety disorders.
  • Structure and Function: The unique structure of this compound, featuring a dimethylamino group, is key to its biological activity. Such substituents can enhance the ability of the drug to cross the blood-brain barrier, increasing its efficacy in neurological applications.
  • Multi-Targeted Activity: Compounds within the phenothiazine family are often designed to act on multiple neurotransmitter receptors, which is essential for their diverse effects in the central nervous system.
  • Research Potential: With ongoing research, compounds like this one are being explored for their potential in treating a variety of conditions beyond just psychiatric disorders, including cancer and infectious diseases due to their ability to selectively target certain cells.

Overall, 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]butan-1-one exemplifies the complexity and versatility of pharmaceutical compounds derived from phenothiazine structures. Its profound impact on medicinal chemistry underscores the importance of such compounds in developing novel therapies.

Synonyms
Butyrylpromazine
3-Butyrylpromazine
3-Butylryl-promazin
20769-36-2
1-(10-(3-(Dimethylamino)propyl)phenothiazin-2-yl)-1-butanone
3-n-Butyryl-10-(3'-dimethylaminopropyl)phenothiazine
DTXSID20174838
1-Butanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-
1-BUTANONE, 1-(10-(3-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YL)-
DTXCID5097329
1-Butanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-(9CI)
RefChem:228822
Oprea1_332219
CHEMBL38869
1-Butanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)- (9CI)