Methylene Blue N-oxide | Solubility of Things

Identification

Molecular formula

C₁₇H₂₀N₄OS

CAS number

1131-00-0

IUPAC name

1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime

State

In room temperature, Methylene Blue N-oxide is typically a solid. Its appearance is distinct due to its vivid dye properties.

Melting point (Celsius)

190.00

Melting point (Kelvin)

463.15

Boiling point (Celsius)

327.00

Boiling point (Kelvin)

600.15

General information

Molecular weight

371.52g/mol

Molar mass

371.5210g/mol

Density

1.3257g/cm³

Appearence

Methylene Blue N-oxide appears as a bluish purple solid. It is usually encountered as a powder or crystalline form and is known for its bright and distinctive color.

Comment on solubility

Solubility of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime

The solubility of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime, particularly in various solvents, is an interesting subject of study given its complex structure. This compound features a phenothiazine moiety that influences its solubility characteristics. Generally, when evaluating the solubility, consider the following factors:

Polarity: The presence of the dimethylamino group contributes to the overall polarity of the compound, which may enhance its solubility in polar solvents such as water and alcohol.
Hydrogen Bonding: The oxime functional group can participate in hydrogen bonding, further impacting its interaction with solvents and solubility.
Temperature Dependence: Solubility can significantly change with temperature. Typically, increasing the temperature leads to an increase in solubility for most organic compounds.
pH Sensitivity: The solubility of this compound may vary with changes in pH, particularly if it carries any ionizable groups under different conditions.

To summarize, the solubility of 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime is likely affected by its polarity and functional groups. It is important to conduct experiments in various solvents to determine the most effective solubility conditions.

Interesting facts

Interesting Facts about 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime

This compound belongs to the class of phenothiazines, which are renowned for their diverse applications in medicinal chemistry, particularly in the realm of psychiatric medications. Here are some fascinating aspects of this compound:

Medicinal Importance: Phenothiazine derivatives have been utilized as antipsychotic agents. This particular compound's unique structure suggests potential interactions in neurological pathways, making it a compound of interest for drug development.
Structure-Activity Relationship: The presence of the dimethylamino group greatly enhances the compound's lipophilicity, which may improve its ability to cross the blood-brain barrier. This is pivotal for compounds aimed at treating central nervous system disorders.
Oxime Functionality: The oxime functional group in this compound is known for its reactivity and versatility in organic synthesis. Oximes can be used as intermediates in synthesizing more complex structures, indicating the potential for further modifications and applications.
Pharmacological Studies: Research into this class of compounds continues to reveal promising therapeutic effects, including antihistaminic and antiemetic properties, making them invaluable in clinical settings.
Research Interests: The unique composition of this compound presents avenues for new research into other potential biological activities beyond its commonly known uses, such as anticancer or antimicrobial effects.

In conclusion, 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one oxime is more than just a chemical entity; it holds the potential for significant contributions to medicinal chemistry and pharmacology. As research progresses, who knows what new properties we might uncover?