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1-(1,2,4-triazol-1-yl)ethanone

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Identification
Molecular formula
C4H5N3O
CAS number
21059-46-1
IUPAC name
1-(1,2,4-triazol-1-yl)ethanone
State
State

At room temperature, 1-(1,2,4-triazol-1-yl)ethanone is typically in a solid crystalline state.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.15
Boiling point (Celsius)
310.80
Boiling point (Kelvin)
583.95
General information
Molecular weight
98.10g/mol
Molar mass
98.1010g/mol
Density
1.1178g/cm3
Appearence

1-(1,2,4-Triazol-1-yl)ethanone appears as a crystalline solid. It is typically colorless to slightly yellow in appearance.

Comment on solubility

Solubility of 1-(1,2,4-triazol-1-yl)ethanone

1-(1,2,4-triazol-1-yl)ethanone, a compound with intriguing properties, exhibits notable solubility characteristics that can be influenced by various factors. Here’s what you need to know:

  • Polarity: The presence of the triazole ring contributes to the overall polarity of the molecule, enhancing its solubility in polar solvents.
  • Solvent Compatibility: It is expected to be more soluble in:
    • Water - due to its polar nature.
    • Alcohols - such as ethanol and methanol.
    • Dimethyl sulfoxide (DMSO) - a highly polar aprotic solvent.
  • Temperature Influence: As with many compounds, increasing temperature can enhance solubility, making it easier for 1-(1,2,4-triazol-1-yl)ethanone to dissolve.
  • pH Levels: The solubility might also be affected by the pH of the solution, particularly if the compound interacts with protons or hydroxyls.

In conclusion, 1-(1,2,4-triazol-1-yl)ethanone's solubility is a dynamic property, largely determined by its molecular structure and the environment in which it is placed. Understanding these factors allows scientists to predict its behavior in various systems, making it a compound of interest in both research and application.

Interesting facts

Interesting Facts about 1-(1,2,4-triazol-1-yl)ethanone

1-(1,2,4-triazol-1-yl)ethanone, commonly referred to in the scientific community for its versatile applications, is a compound that showcases the intersection of organic chemistry and pharmacology. This compound features a triazole ring structure, which is known for its role in various biological activities and medicinal applications.

Key Highlights:

  • Pharmacological Potential: The presence of the triazole moiety makes this compound of great interest in drug development, particularly in antifungal agents and other therapeutic candidates.
  • Versatile Synthesis: The synthesis of 1-(1,2,4-triazol-1-yl)ethanone can be achieved through various methods, making it accessible for research purposes. It's an excellent example of how organic synthesis can creatively utilize functional groups.
  • Chemical Behavior: Compounds containing the triazole structure often exhibit interesting chemical behaviors, including coordination with metal ions and participation in various organic reactions, which can lead to the formation of derivatives with enhanced properties.
  • Biological Role: Research indicates that triazole-derived compounds may influence enzyme activity, opening avenues for investigating their roles in biochemistry and cellular processes.

As a scientist or chemistry student, exploring the mechanics of 1-(1,2,4-triazol-1-yl)ethanone could lead to numerous discussions around its synthesis, feature advantages in drug design, and ultimately contribute to understanding its role in medicinal chemistry. The compound not only represents an exciting area of study but also signifies the rich tapestry of organic compounds that continue to shape the pharmaceutical landscape.

Synonyms
15625-88-4
1-(1H-1,2,4-triazol-1-yl)ethan-1-one
1-Acetyl-1,2,4-triazole
1-(1H-1,2,4-Triazol-1-yl)ethanone
1-(1,2,4-triazol-1-yl)ethanone
1-ACETYL-1H-1,2,4-TRIAZOLE
MFCD18807045
Ethanone, 1-(1H-1,2,4-triazol-1-yl)-
1-[1,2,4]Triazol-1-ylethanone
N-acetyl-1,2,4-triazol
SCHEMBL9427893
YSCK0318
DTXSID70166066
GLGDTYAVPSJOSQ-UHFFFAOYSA-N
1H-1,2,4-triazole, 1-acetyl-
AKOS026674963
FK-0043
CS-0447429
E84466
EN300-6478866
1H-1,2,4-Triazole,1-acetyl-(6CI,7CI,8CI,9CI)
InChI=1/C4H5N3O/c1-4(8)7-3-5-2-6-7/h2-3H,1H