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Androstenedione

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Identification
Molecular formula
C19H26O2
CAS number
63-05-8
IUPAC name
1-[(17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]propan-1-one
State
State

At room temperature, androstenedione is in a solid state.

Melting point (Celsius)
172.20
Melting point (Kelvin)
445.30
Boiling point (Celsius)
369.15
Boiling point (Kelvin)
642.30
General information
Molecular weight
286.41g/mol
Molar mass
286.4090g/mol
Density
1.0708g/cm3
Appearence

Androstenedione appears as a white crystalline powder. It lacks a significant odor and is known for its solubility in ethanol and ether, while it has limited solubility in water.

Comment on solubility

Solubility of 1-[(17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]propan-1-one

The solubility of 1-[(17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]propan-1-one is a point of interest due to its complex structure. Here are some key considerations regarding its solubility:

  • Solvent Type: The solubility of organic compounds, like this one, typically depends on the type of solvent. It tends to be more soluble in non-polar organic solvents than in polar solvents due to its hydrophobic characteristics.
  • Hydroxyl Groups: The presence of hydroxyl (-OH) groups in the structure may enhance solubility in polar solvents to an extent, as these groups can engage in hydrogen bonding.
  • Molecular Weight: With its relatively high molecular weight and bulky structure, solubility may be limited in lower molecular weight solvents.
  • Temperature Effects: Generally, increasing the temperature can improve solubility, but the extent to which this applies to this specific compound requires experimental verification.

In conclusion, the solubility behavior of this compound is influenced by multiple factors, making it an intricate subject of study. The impact of its functional groups and structural complexity is vital in determining its interactions with different solvents.

Interesting facts

Interesting Facts about 1-[(17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]propan-1-one

This compound, often referred to in the context of steroid chemistry, showcases a fascinating and complex structure. Here are some intriguing aspects:

  • Natural Occurrence: This compound is a derivative of naturally occurring steroids, which play critical roles in various biological processes. It can often be found in certain plants or animal tissues, indicating a significant biological function.
  • Pharmacological Potential: Due to its hydroxyl groups and specific carbon skeleton, it holds promise in pharmaceutical research, particularly in hormone replacement therapies and anti-inflammatory treatments.
  • Stereochemistry: The (17R) designation indicates a specific stereoisomer, which is critical for biological activity. This emphasizes the importance of stereochemistry in drug design for achieving desired physiological effects.
  • Mechanistic Studies: Research involving this compound can provide insights into mechanisms of action for other steroids, enhancing our understanding of metabolism and hormone signaling pathways.

As scientists delve deeper into the properties and applications of such compounds, the potential for new therapeutic agents continues to expand. A quote from Victor J. Meyer resonates in this field: "Chemistry knows no boundaries." This underscores the relentless pursuit and exploration of complex molecules like this compound in the quest for advancements in medicine and biology.

Overall, 1-[(17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]propan-1-one serves as a prime example of how intricate molecular structures can have significant implications in science and health.