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Nisin

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Identification
Molecular formula
C143H230N42O37S7
CAS number
1414-45-5
IUPAC name
1-[19-amino-7-(2-amino-2-oxo-ethyl)-10-(3-amino-3-oxo-propyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[5-amino-1-[(2-amino-2-oxo-ethyl)carbamoyl]pentyl]pyrrolidine-2-carboxamide
State
State

At room temperature, nisin is typically a solid. It is most commonly stored as a lyophilized powder, which is stable and easy to handle in laboratory and industrial settings.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
3354.07g/mol
Molar mass
3 354.0720g/mol
Density
1.2350g/cm3
Appearence

Nisin is a polypeptide that is naturally occurring and is characterized by its off-white powdery appearance. It is frequently used as a food preservative due to its antibiotic properties. When dissolved in solution, it is colorless.

Comment on solubility

Solubility of 1-[19-amino-7-(2-amino-2-oxo-ethyl)-10-(3-amino-3-oxo-propyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[5-amino-1-[(2-amino-2-oxo-ethyl)carbamoyl]pentyl]pyrrolidine-2-carboxamide (C143H230N42O37S7)

The solubility of the compound is a fascinating topic due to its complex structure and multiple functional groups. Understanding solubility involves considering the interaction of the compound with solvents at the molecular level, which can be influenced by factors such as polarity, hydrogen bonding, and steric hindrance.

Key considerations regarding the solubility of this compound include:

  • Polarity: The presence of numerous polar amino and carboxamide groups suggests that the compound may exhibit good solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The potential for extensive hydrogen bonding interactions with water can enhance solubility; however, steric factors may play a role in limiting accessibility.
  • Overall Size: The large molecular weight (C143H230N42O37S7) suggests that solubility might decrease with increasing solvent viscosity.

As with many complex compounds, the exact solubility characteristics can only be definitively determined through experimental analysis. It is essential to utilize a variety of solvents to assess how this compound behaves under different conditions. "Solubility is not a one-size-fits-all characteristic!" Thus, empirical studies play a crucial role in understanding how and where this compound can dissolve effectively.

Interesting facts

Interesting Facts about 1-[19-amino-7-(2-amino-2-oxo-ethyl)-10-(3-amino-3-oxo-propyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[5-amino-1-[(2-amino-2-oxo-ethyl)carbamoyl]pentyl]pyrrolidine-2-carboxamide

This fascinating compound represents a multi-functional architecture which is indicative of a new class of therapeutic agents. Here are several notable aspects:

  • Complex Structure: The compound is characterized by a highly intricate structure, containing multiple functional groups and a cyclic framework that contribute to its potential biochemical activity.
  • Potential Applications: Given its amino acid components, there is a significant interest in the therapeutic implications of this compound. It's being explored in fields such as drug discovery, particularly for targeted therapies in cancer research.
  • Inhibition Mechanism: Compounds like this often utilize specific inhibitors that can disrupt disease processes at a molecular level, which may include binding to various enzymes or receptors involved in disease pathways.
  • Interdisciplinary Research: The complexity and functionality of this compound make it a subject of study not only in organic chemistry but also in pharmacology and medicinal chemistry, illustrating the importance of interdisciplinary approaches in modern science.
  • Quoting the Experts: As noted by several researchers, “The development of complex molecules like this holds the key to unlocking the next generation of therapeutics.” This highlights the ongoing investment in research and development in this area.

In summary, the compound’s unique architecture and potential for impacting human health make it a compelling subject of study for scientists and researchers alike. Future investigations are likely to shed light on its mechanisms and effectiveness in various biomedical applications.

Synonyms
FELYPRESSIN
Felypressin Acetate
Felipresina
56-59-7
NCGC00182033-01
SCHEMBL1650172
Octapressin; Felypressin; PLV-2
BCP27701
AKOS026750541
L001276