1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine

Identification

Molecular formula

C₁₂H₉N₃S

CAS number

5301-96-2

IUPAC name

1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine

State

At room temperature, this compound is a solid. It tends to be stable under normal conditions and is usually handled as a powder or fine crystalline material.

Melting point (Celsius)

168.00

Melting point (Kelvin)

441.15

Boiling point (Celsius)

275.00

Boiling point (Kelvin)

548.15

General information

Molecular weight

240.30g/mol

Molar mass

240.3000g/mol

Density

1.3000g/cm³

Appearence

The compound appears as a solid crystalline substance. It typically forms fine crystals or powder with a possible light gray or beige coloration, depending on purity and handling conditions.

Comment on solubility

Solubility of 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine

The solubility of 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine is an intriguing aspect of its chemical behavior. This compound, characterized by the fusion of an indole and a thiazole structure, displays a solubility profile that can be influenced by various factors. Here are some key points to consider:

Polarity: The presence of both the indole and thiazole rings gives this compound a moderate to low polarity, which may affect its interaction with polar solvents.
Solvent Interaction: Generally, the solubility in common solvents can be summarized as follows:
- Water: Likely low solubility due to the hydrophobic nature of the indole moiety.
- Organic Solvents: Better solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) due to favorable interactions.
Temperature Effects: Increased temperature may enhance solubility in organic solvents, making it essential to consider thermodynamic factors.

In conclusion, while the solubility of 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine may not be exceptionally high in aqueous solutions, it exhibits *potentially advantageous solubility characteristics* in organic environments, which could be useful for various applications in research and industry.

Interesting facts

Exploring 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine

1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine is a fascinating compound that exemplifies the intersection of two rich fields of organic chemistry: indoles and thiazoles. This compound serves as a great example of how the structural diversity of organic molecules can lead to a wide range of biological activities. Here are some interesting facts about this compound:

Indole Derivative: The presence of the indole ring in this compound links it to a class of compounds known for their significant effects in pharmacology, including antidepressant, antitumor, and anti-inflammatory properties.
Thiazole Impact: Incorporating thiazole not only enhances the bioactivity of indole but also contributes to the compound's potential in medicinal chemistry. Compounds containing thiazole rings often exhibit antimicrobial and antifungal activity.
Diverse Applications: The unique structure of 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine allows for potential applications in various fields, including pharmaceuticals, agriculture, and materials science.
Synthesis: The synthesis of this compound usually involves multi-step reactions that can be optimized using green chemistry principles, providing an excellent case study in sustainable organic synthesis.
Research Interest: Due to the compound's structural complexity and biological significance, it continues to be a subject of ongoing research aimed at understanding its mechanisms and improving its efficacy in therapeutic applications.

In summary, 1-(1H-indol-3-yl)-N-thiazol-2-yl-methanimine isn't just another compound; it embodies the rich potential of organic chemistry in creating innovative solutions and therapeutics. As you delve deeper into its study, you may discover even more about its capabilities and applications that resonate with advancements in science.

Synonyms

Oprea1_173536

Oprea1_446711

HMS2300P16