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Indole-3-propylammonium acetate

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Identification
Molecular formula
C11H15N2C2H4O2
CAS number
Not Available
IUPAC name
1-(1H-indol-3-ylmethyl)propylammonium;acetate
State
State

At room temperature, indole-3-propylammonium acetate is typically in a solid state, presenting as crystalline material.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
237.90
Boiling point (Kelvin)
511.05
General information
Molecular weight
246.32g/mol
Molar mass
246.3180g/mol
Density
1.0500g/cm3
Appearence

Indole-3-propylammonium acetate appears as a white to off-white crystalline powder. It may also appear as a fine granular solid depending on the specific preparation method.

Comment on solubility

Solubility of 1-(1H-indol-3-ylmethyl)propylammonium Acetate

The solubility of 1-(1H-indol-3-ylmethyl)propylammonium acetate typically exhibits interesting characteristics due to its unique molecular structure. This compound, being a quaternary ammonium salt, generally shows good solubility in polar solvents, particularly:

  • Water: The presence of the ammonium group enhances solvation, allowing it to dissolve well.
  • Alcohols: Compounds like ethanol or methanol may also effectively solubilize it.

However, the solubility can be influenced by several factors:

  1. Temperature: Increased temperatures often enhance solubility rates.
  2. pH Levels: As an acetate salt, the pH of the solution can impact dissociation and solubility.
  3. Concentration: Saturation levels will ultimately determine the extent of solubility.

In conclusion, as a quaternary ammonium salt, 1-(1H-indol-3-ylmethyl)propylammonium acetate shows *strong potential for solubility in various polar solvents*, making it useful for various applications, including pharmacological contexts where solubility plays a crucial role. It is essential to consider the solvent environment and external conditions to *maximize the solubility* of this compound.

Interesting facts

Interesting Facts About 1-(1H-indol-3-ylmethyl)propylammonium Acetate

1-(1H-indol-3-ylmethyl)propylammonium acetate is a fascinating compound known for its association with biological activities and potential therapeutic applications. Here are some intriguing aspects:

  • Indole Structure: The presence of the indole ring, a structure common in many biologically active compounds, indicates that this compound may exhibit significant interaction with biological systems. Indoles are known for their roles in neurotransmission, and many of them are naturally occurring in plants.
  • Pharmacological Potential: Compounds similar to this acetate derivative have shown promise in modulating serotonin receptors, which could play a role in mood regulation. Due to its structural properties, researchers explore its potential in the treatment of anxiety and depression.
  • Ammonium Functionality: The ammonium group in the compound enhances solubility in aqueous environments, which may translate into increased bioavailability in therapeutic applications. This functional group is often crucial in drug formulation.
  • Acetate Salt: Being an acetate salt, it may exhibit unique properties compared to its neutral form. The acetate group can influence both the stability and solubility of the compound, either enhancing or limiting its effects depending on the context of use.
  • Research Interest: This compound is also of interest in the field of organic synthesis and medicinal chemistry, prompting further exploration of its derivatives and analogs to enhance efficacy and reduce side effects in pharmacological applications.

Overall, 1-(1H-indol-3-ylmethyl)propylammonium acetate stands out as a compound that bridges the gap between organic chemistry and pharmacology, making it a subject of exciting research and discovery.