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6-(2-Aminopropyl)indole

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Identification
Molecular formula
C11H14N2
CAS number
22196-33-2
IUPAC name
1-(1H-indol-6-yl)propan-2-amine
State
State

At room temperature, 6-(2-Aminopropyl)indole is typically found in solid form. The compound’s stability and solid state make it convenient for manufacturing, storage, and various applications.

Melting point (Celsius)
147.50
Melting point (Kelvin)
420.65
Boiling point (Celsius)
244.30
Boiling point (Kelvin)
517.45
General information
Molecular weight
174.25g/mol
Molar mass
174.2470g/mol
Density
1.1020g/cm3
Appearence

6-(2-Aminopropyl)indole typically appears as an off-white to pale yellow solid. Its exact appearance can vary dependent on the purity and specific form of the compound that is available, often influenced by the presence of impurities or additional ingredients used in specific applications.

Comment on solubility

Solubility of 1-(1H-indol-6-yl)propan-2-amine

The solubility of 1-(1H-indol-6-yl)propan-2-amine is quite interesting and can be evaluated based on several factors. Here are some key points regarding its solubility:

  • Polarity: The compound has both hydrophobic and hydrophilic characteristics, given its indole structure and the amine functional group.
  • Solvent Compatibility: It is generally more soluble in organic solvents such as ethanol or methanol than in water due to its aromatic nature.
  • Influence of pH: The solubility may increase in acidic conditions, where the amine group can become protonated, enhancing solubility in aqueous solutions.
  • Temperature Effects: As with many organic compounds, increased temperature often leads to enhanced solubility.

In practical applications, it is often noted that general solubility trends can vary significantly based on specific conditions. Therefore, testing under relevant conditions is vital. Understanding solubility plays a crucial role in the formulation and application of this compound in various fields, including pharmaceuticals.

Interesting facts

Interesting Facts about 1-(1H-Indol-6-yl)propan-2-amine

1-(1H-Indol-6-yl)propan-2-amine is a fascinating compound that bridges the worlds of organic chemistry and pharmacology. Below are some engaging details that highlight its significance:

  • Structure and Stability: The compound features a unique indole structure, which is known for its aromatic properties and stability. This structural characteristic plays a vital role in its interactions with biological systems.
  • Biological Importance: Compounds like 1-(1H-Indol-6-yl)propan-2-amine often exhibit bioactive properties, making them subjects of interest for drug development. Their potential applications include acting as antidepressants and in the treatment of various neuropsychiatric disorders.
  • Mechanism of Action: It is believed that the compound may influence the serotonergic system in the brain, similar to other indole derivatives, which could result in mood modulation and emotional stability.
  • Synthetic Pathways: The synthesis of this compound can involve several organic reactions such as amination and alkylation processes, which are intriguing for students as they explore the versatility of organic synthesis methods.
  • Research Potential: As a relatively lesser-known entity in the vast world of chemical compounds, 1-(1H-Indol-6-yl)propan-2-amine offers a rich avenue for scientific exploration and research, inviting chemists to investigate its properties further.

In summary, 1-(1H-Indol-6-yl)propan-2-amine serves as an excellent example of how organic molecules can play a substantial role in biological systems. Its intriguing structure and potential pharmacological properties make it a compelling subject for both chemists and pharmacologists alike.

Synonyms
6-(2-Aminopropyl)indole
6-Aminopropylindole
(2-(1H-Indol-6-yl)-1-methylethyl)amine
[2-(1H-Indol-6-yl)-1-methylethyl]amine
27230C15B7
UNII-27230C15B7
INDOLE, 6-(2-AMINOPROPYL)-
1H-Indole-6-ethanamine, alpha-methyl-
1H-INDOLE-6-ETHANAMINE, .ALPHA.-METHYL-
RefChem:103993
6-API
UNII-M7C77J017A
21005-63-0
1-(1H-indol-6-yl)propan-2-amine
alpha-methyl-1H-indole-6-ethanamine
6-(2'-amino-propyl) indole
SCHEMBL4501771
DTXSID501030112
MFCD08453197
AKOS006290701
PD019451
HY-172028
NS00017626
Q4641521