1-[(1R,10R,16R,20S)-1-fluoro-23-hydroxy-2,18,18,21-tetramethyl-7-phenyl-17,19-dioxa-6,7-diazahexacyclo[11.10.0.02,10.04,8.014,21.016,20]tricosa-4(8),5-dien-20-yl]-2-hydroxy-ethanone

Identification

Molecular formula

C₂₆H₃₂FNO₄

CAS number

n/a

IUPAC name

1-[(1R,10R,16R,20S)-1-fluoro-23-hydroxy-2,18,18,21-tetramethyl-7-phenyl-17,19-dioxa-6,7-diazahexacyclo[11.10.0.02,10.04,8.014,21.016,20]tricosa-4(8),5-dien-20-yl]-2-hydroxy-ethanone

State

At room temperature, the compound is in a solid state, with a crystalline structure.

Melting point (Celsius)

233.00

Melting point (Kelvin)

506.15

Boiling point (Celsius)

340.00

Boiling point (Kelvin)

613.15

General information

Molecular weight

471.55g/mol

Molar mass

471.5480g/mol

Density

1.3285g/cm³

Appearence

The compound appears as a white crystalline solid, notable for its structural complexity including both fluorine and a phenyl group, contributing to its stability and appearance.

Comment on solubility

Solubility of 1-[(1R,10R,16R,20S)-1-fluoro-23-hydroxy-2,18,18,21-tetramethyl-7-phenyl-17,19-dioxa-6,7-diazahexacyclo[11.10.0.02,10.04,8.014,21.016,20]tricosa-4(8),5-dien-20-yl]-2-hydroxy-ethanone

The solubility of this complex compound is influenced by several factors. Given its intricate structure and the presence of diverse functional groups, we can make some observations:

Polarity: The presence of hydroxyl groups (-OH) typically enhances solubility in polar solvents such as water.
Hydrophobic Regions: The tetracyclic nature and bulky phenyl group suggest that while certain regions may interact favorably with water, other regions may exhibit hydrophobic characteristics, potentially leading to lower solubility in water.
Solvent Compatibility: One would expect higher solubility in organic solvents such as methanol or ethanol due to the overall structure’s ability to interact with non-polar and polar parts of these solvents.

In general, it could be summarized that:

"The complex interplay of hydrophilic and hydrophobic properties determines the solubility in varying solvents."

In summary, the solubility of this compound is likely to be variable and dependent on the solvent system chosen, emphasizing the need for experimental determination for precise applications.

Interesting facts

Interesting Facts about 1-[(1R,10R,16R,20S)-1-fluoro-23-hydroxy-2,18,18,21-tetramethyl-7-phenyl-17,19-dioxa-6,7-diazahexacyclo[11.10.0.02,10.04,8.014,21.016,20]tricosa-4(8),5-dien-20-yl]-2-hydroxy-ethanone

This compound, often abbreviated for convenience, is a remarkable example of the complexity found in organic chemistry, showcasing a myriad of functional groups and a unique three-dimensional structure. Its intricate design not only embodies *synthetic excellence* but also *biological significance*. Here are some fascinating aspects to consider:

Fluorine Atom: The presence of a fluorine atom in its structure suggests potential applications in medicinal chemistry, as fluorinated compounds often exhibit improved metabolic stability and bioactivity.
Hydroxyl Groups: The two hydroxyl (–OH) groups enhance its solubility and reactivity, allowing it to participate in a variety of chemical reactions, which could lead to interesting pharmacological properties.
Tetracyclic Nature: The tetracyclic core indicates *structural rigidity*, which is critical for maintaining specific conformations that can be essential for biological interactions.
Potential Applications: The specific stereochemistry and substituents suggest this compound could have utility in fields ranging from materials science to pharmaceutical development, particularly in targeting systems or pathways with precision.

Not only does this compound encapsulate the beauty of organic composites, but it also serves as a reminder of the intricate relationship between molecular structure and function. As one prominent chemist once said, "The study of chemistry reveals the underlying principles that connect the materials of our world." This compound is a perfect embodiment of that sentiment, offering a glimpse into the wonders of chemical innovation.

Through further research and exploration of such complex compounds, scientists may unveil not only novel applications but also deeper insights into the mechanisms of life itself.