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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
1-[(1R,5R,6S,9S,12R)-9,12-dihydroxy-6,16-dimethyl-10,19-dioxa-16-azahexacyclo[12.5.3.15,9.01,14.02,11.06,11]tricosa-2,21-dien-22-yl]ethyl 5-ethyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
State
State

Erythromycin is typically found in a solid state as a crystalline powder at room temperature.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
727.30
Boiling point (Kelvin)
1 000.50
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2300g/cm3
Appearence

Erythromycin appears as a white or slightly yellow crystalline powder. It is often odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of 1-[(1R,5R,6S,9S,12R)-9,12-dihydroxy-6,16-dimethyl-10,19-dioxa-16-azahexacyclo[12.5.3.15,9.01,14.02,11.06,11]tricosa-2,21-dien-22-yl]ethyl 5-ethyl-2,4-dimethyl-1H-pyrrole-3-carboxylate

The solubility of this complex compound can be influenced by various factors, primarily due to its intricate molecular structure. Here are some key considerations:

  • Polarity: The presence of hydroxyl groups in the structure usually suggests a higher degree of polarity, which may facilitate solubility in polar solvents such as water and alcohols.
  • Functional Groups: The five-membered and cyclic structures contribute to the compound's unique interactions with solvents.
  • Hydrogen Bonding: With multiple hydroxyl groups, the ability to form hydrogen bonds can enhance solubility in aqueous environments.
  • Hydrophobic Interactions: Conversely, the large hydrophobic regions within the compound may hinder solubility in polar solvents.

In summary, while this compound potentially exhibits moderate to good solubility in polar solvents, the extent of solubility will vary significantly based on the solvent's nature and environmental conditions. For a comprehensive understanding, empirical solubility tests in various solvent systems may be necessary to elucidate the actual solubility profile.

Interesting facts

Interesting Facts about the Compound

This compound, a complex organic molecule, displays a fascinating structure that embodies the richness of chemistry. Here are some noteworthy aspects:

  • Structural Complexity: The compound features a unique hexacyclic framework, characterized by multiple fused rings. This structural diversity is indicative of its potential biological activity and interaction with various biomolecules.
  • Natural Sources: Compounds with similar architectures are often found in nature, especially in plants and fungi. They may play vital roles in ecological interactions and can influence the behaviors of insects and other organisms.
  • Potential Applications: Due to its intricate design, this molecule could be explored for therapeutic applications, including pharmaceuticals and agrochemicals. Compounds of this nature are often investigated for their activity against specific diseases.
  • Stereochemistry: The stereochemical aspects of the compound highlight the importance of chirality in medicinal chemistry. The different spatial arrangements could significantly impact the biological activity and effectiveness of the drug derived from it.
  • Targeted Studies: Researchers focus on compounds with complex structures to develop new drug candidates. This involves studying their synthesis, mechanism of action, and biological targets.

In the words of renowned chemist Linus Pauling, "Most of the world's great achievements have come from people who have kept on trying when there seemed to be no hope at all." This sentiment resonates with the ongoing exploration of such multifaceted compounds, opening avenues for future discoveries that may benefit society as a whole.

Overall, this compound exemplifies the beauty of organic chemistry, where intricate designs hold the potential for significant scientific advancements.

Synonyms
BRN 1613496
23509-22-0
BATRACHOTOXININ A, 20-alpha-(2,4-DIMETHYL-5-ETHYL-1H-PYRROLE-3-CARBOXYLATE)
RefChem:320981
DTXSID60946197
1-(9,12-Dihydroxy-2,11a-dimethyl-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-7H-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepin-14-yl)ethyl 5-ethyl-2,4-dimethyl-1H-pyrrole-3-carboxylate