Skip to main content

Bupropion

ADVERTISEMENT
Identification
Molecular formula
C13H18ClNO1
CAS number
31677-93-7
IUPAC name
1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one
State
State

At room temperature, Bupropion is a solid substance.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
391.70
Boiling point (Kelvin)
664.90
General information
Molecular weight
239.74g/mol
Molar mass
239.7400g/mol
Density
1.2950g/cm3
Appearence

Bupropion appears as a white, crystalline powder. It is essentially odorless and has a bitter taste.

Comment on solubility

Solubility of 1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one

The compound 1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one, characterized by its complex structure and functional groups, exhibits intriguing solubility properties. Understanding its solubility is crucial for applications in pharmaceuticals, as it can affect both bioavailability and formulation parameters.

Key Aspects of Solubility:

  • Polarity: The presence of the diethylamino group and an ether linkage could impart some degree of polarity to the molecule. Polar compounds tend to be more soluble in polar solvents.
  • Hydrophobic Characteristics: The long carbon chain in the butanone structure suggests potential hydrophobic interactions, which may lead to lower solubility in water compared to organic solvents.
  • Solvent Trends: This compound may exhibit enhanced solubility in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or acetone while showing limited solubility in water due to the overall hydrophobic nature.
  • Temperature Dependence: Like many organic compounds, solubility may also increase with temperature, suggesting that heat can facilitate dissolution in certain solvents.

In summary, the solubility of 1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one is influenced by various factors including polarity, hydrophobic regions, and solvent choice. Each of these elements plays a vital role in determining how and where this compound can be effectively used in practical applications.

Interesting facts

Interesting Facts about 1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one

This complex organic compound, known for its intriguing structure and potential applications, is a fascinating subject of study in the field of chemistry. Here are some captivating insights:

  • Diverse Applications: This compound has shown promise in various fields, particularly in medicinal chemistry. It is often explored for its potential as a pharmaceutical agent due to the presence of the nitro group, which is known to enhance biological activity.
  • Functional Groups: The molecular structure features a diethylamino substituent, which can significantly influence solubility and interactions with biological targets. This functional group can facilitate the compound's ability to cross lipid membranes, making it potentially useful in drug delivery systems.
  • Role of Nitro Group: The presence of the nitro group in the aromatic ring provides unique reactivity and biological properties. Compounds with nitro groups are often investigated for their roles as antimicrobial and anticancer agents, adding to their relevance in therapeutic research.
  • Chemical Complexity: The compound’s elaborate structure combines various functionalities, which can lead to structure-activity relationships (SAR). Understanding these relationships is crucial in the design of new derivatives that can optimize desired effects while minimizing side effects.
  • Analytical Studies: Researchers often use advanced techniques such as NMR spectroscopy and mass spectrometry to study compounds like this one. These methods aid in understanding the compound’s behavior in different environments and its interactions at a molecular level.

In summary, 1-[2-[2-(diethylamino)ethoxy]-3-nitro-phenyl]butan-1-one exemplifies the intricate relationship between chemical structure and function. Its diverse applications and complex behavior make it a valuable subject for further research within the scientific community.