Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone
State
State

At room temperature, lidocaine is typically in a solid state when in its pure form.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3380g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is a white crystalline powder. It is often supplied in solution form, appearing as a clear liquid in vials or ampoules for medical use. In its solid form, it might appear as a fine, white to slightly yellow powder.

Comment on solubility

Solubility of 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone

The solubility of 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone can be influenced by several factors such as its molecular structure, temperature, and the solvent used. In general, compounds that contain polar functional groups tend to exhibit improved solubility in polar solvents, while non-polar solvents serve better for non-polar compounds.

Key Points on Solubility:

  • Polarity: The dimethylamino group contributes to some polarity in the molecule, which may enhance its solubility in polar solvents like water or alcohols.
  • Solvent Compatibility: This compound may dissolve readily in organic solvents such as methanol or ethanol due to its ether and amine functionalities.
  • Temperature Effect: Higher temperatures often increase the solubility of organic compounds; thus, heating the solution could further enhance solubility.
  • Concentration Considerations: Concentrations may also play a role; saturation levels can differ significantly depending on the solvent used.

It is essential to conduct empirical solubility tests to determine the exact solubility behavior of 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone in various environments, as theoretical predictions may not always hold true. Remember, “solubility is a key property affecting pharmacokinetics and bioavailability,” making it a crucial aspect when considering applications in pharmaceuticals.

Interesting facts

Interesting Facts about 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone

This intriguing compound, known as 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone, is a member of the ketone family and has garnered interest in various fields of chemistry and pharmacology. Here are some enlightening points about this compound:

  • Structural Complexity: The structure features a ketone functional group attached to a phenyl ring, adorned with an ethoxy group and a dimethylamino moiety. This structural design highlights the compound's potential for diverse interactions in biological systems.
  • Applications in Research: Compounds like this one are often used in research related to drug design and development. Their unique functional groups may lead to interesting interactions with biological targets, making them valuable in medicinal chemistry.
  • Biological Activity: The presence of the dimethylamino group typically enhances the compound’s solubility and may influence its bioactivity, offering promising avenues for therapeutic applications.
  • Synthetic Routes: The synthesis of 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone can be approached through various chemical reactions, highlighting the importance of knowledge in synthetic organic chemistry for the creation of complex molecules.
  • Pharmacophores: Understanding the pharmacophore of this compound can reveal how particular structural features contribute to its effectiveness in modulating biological pathways, which is crucial for drug discovery.

As research continues, compounds like 1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone remain at the forefront of scientific investigation, bridging the gap between chemistry and biological sciences.

Synonyms
2089-20-5
ACETOPHENONE, 2'-(2-(DIMETHYLAMINO)ETHOXY)-
BRN 1961686
2'-(2-(Dimethylamino)ethoxy)acetophenone
DTXSID90175034
4-08-00-00322 (Beilstein Handbook Reference)
DTXCID1097525
1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone
Ethanone, 1-[2-[2-(dimethylamino)ethoxy]phenyl]-
SCHEMBL6669660
PKEROHUSQKVCKS-UHFFFAOYSA-N
AKOS000173987
1-[2-(2-dimethylamino-ethoxy)-phenyl]-ethanone