Skip to main content

1-[2-(2-pyridyl)ethyl]indoline

ADVERTISEMENT
Identification
Molecular formula
C15H16N2
CAS number
70110-10-2
IUPAC name
1-[2-(2-pyridyl)ethyl]indoline
State
State
The compound is typically a liquid at room temperature.
Melting point (Celsius)
11.00
Melting point (Kelvin)
284.15
Boiling point (Celsius)
203.80
Boiling point (Kelvin)
476.95
General information
Molecular weight
222.31g/mol
Molar mass
222.3080g/mol
Density
1.1477g/cm3
Appearence

The compound typically appears as a colorless to pale yellow liquid.

Comment on solubility

Solubility of 1-[2-(2-pyridyl)ethyl]indoline

1-[2-(2-pyridyl)ethyl]indoline is an intriguing compound with noteworthy solubility characteristics. Understanding its solubility can provide insights into its potential applications and behavior in different environments. Here are some critical points to consider:

  • Solvent Interaction: The solubility of 1-[2-(2-pyridyl)ethyl]indoline is significantly influenced by the polarity of the solvent. It tends to dissolve well in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) due to favorable interactions between the solvent and the aromatic rings present in the structure.
  • Water Solubility: This compound exhibits limited solubility in water. The presence of the indoline and pyridine moieties creates a nonpolar environment that hinders its interaction with polar water molecules.
  • Temperature Effects: As with many organic compounds, increasing the temperature can enhance solubility, allowing for better intermolecular interactions and overcoming energy barriers associated with dissolution.
  • pH Dependence: The solubility may also vary with changes in pH, particularly because the nitrogen atoms in the pyridine and indoline rings can become protonated under acidic conditions, which can alter solubility profiles.

In summary, while 1-[2-(2-pyridyl)ethyl]indoline demonstrates good solubility in organic solvents, it remains poorly soluble in water, highlighting its unique functional characteristics. As emphasized, factors like solvent choice, temperature, and pH play pivotal roles in its solubility behavior. Understanding these parameters is crucial for applications in fields ranging from pharmaceuticals to materials science.

Interesting facts

Interesting Facts about 1-[2-(2-pyridyl)ethyl]indoline

1-[2-(2-pyridyl)ethyl]indoline is a fascinating compound that merges elements of both organic synthesis and medicinal chemistry. Here are some engaging insights to appreciate its significance:

  • Structural Uniqueness: The compound features a distinctly derived indoline structure, which is an important component for various nitrogen-containing heterocycles.
  • Biological Activity: Thanks to its 2-pyridyl substituent, 1-[2-(2-pyridyl)ethyl]indoline is of interest in the pharmaceutical industry for its potential biological activities, including antifungal and anti-inflammatory properties.
  • Versatile Intermediates: This compound serves as an intermediate in the synthesis of more complex compounds, paving the way for further research and development in drug design.
  • Coordination Chemistry: The nitrogen atoms in its structure can facilitate coordination with metal ions, making it valuable in the development of metallo-drugs.
  • Studies and Applications: Researchers have been investigating its efficacy in various therapeutic applications, exemplifying the enduring connection between organic compounds and their potential to impact health and medicine.

In summary, 1-[2-(2-pyridyl)ethyl]indoline is not just an interesting molecular structure but a gateway to understanding the broader realms of chemistry, especially in relation to drug discovery and development. Its distinct features and biological significance make it a compound worthy of study in contemporary scientific research.

Synonyms
INDOLINE, 1-(2-(2-PYRIDYL)ETHYL)-
BRN 0478326
1-(2-(2-Pyridyl)ethyl)indoline
PE-10
14845-02-4
1-beta-(Pyridyl-2')-ethyl-2,3-dihydroindole
DTXSID00163987
5-22-09-00373 (Beilstein Handbook Reference)
DTXCID0086478
pyridylethylindoline
SCHEMBL29374038