Skip to main content

Carvedilol

ADVERTISEMENT
Identification
Molecular formula
C24H26N2O4
CAS number
72956-09-3
IUPAC name
1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]amino]propan-2-ol
State
State

At room temperature, Carvedilol is a solid.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
492.15
Boiling point (Kelvin)
765.30
General information
Molecular weight
406.49g/mol
Molar mass
406.4860g/mol
Density
1.2280g/cm3
Appearence

Carvedilol is generally found as a white to almost white crystalline powder. It can appear as a crystalline, light-sensitive compound which may exhibit poor solubility in water but is better soluble in organic solvents.

Comment on solubility

Solubility Characteristics

The compound 1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]amino]propan-2-ol exhibits intriguing solubility properties that are influenced by its unique molecular structure.

Factors Affecting Solubility

Several factors contribute to the solubility of this compound:

  • Molecular Polarity: As the compound contains multiple functional groups, including hydroxyl (-OH) and amino (-NH2), it exhibits notable polarity, enhancing its affinity for polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds allows the compound to interact more favorably with solvent molecules, improving solubility.
  • Structural Complexity: The presence of the benzodioxin moiety may introduce steric hindrance that could affect solubility in organic solvents.

As a result, it is expected that this compound will have a higher solubility in polar solvents compared to non-polar ones. Furthermore, it is often classified as a moderately soluble compound, making it suitable for various applications where solubility is a critical factor. Overall, the intricate balance between polarity and molecular structure plays a pivotal role in determining its solubility characteristics.

Interesting facts

Exploring 1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]amino]propan-2-ol

This intriguing compound possesses a complex structure that makes it a fascinating subject for research and study. Here are some noteworthy facts about this compound:

  • Pharmaceutical Potential: 1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]amino]propan-2-ol has been investigated for its potential applications in the pharmaceutical industry. Its unique structure may contribute to specific biological activities, opening doors for drug development.
  • Structure-Activity Relationship: Studying this compound helps chemists understand the relationship between its chemical structure and biological activity. The benzodioxin moiety plays a significant role in influencing its pharmacological properties.
  • Intermolecular Interactions: The presence of multiple functional groups allows for interesting intermolecular interactions, which can affect solubility and reactivity. Understanding these interactions is crucial for potential therapeutic applications.
  • Research Applications: This compound serves as a model for synthesizing and analyzing other drugs, offering insights into improved design and efficacy of new pharmaceutical agents.
  • Natural Product Inspiration: The compound's structure suggests inspiration from natural products, prompting researchers to explore similar compounds found in nature and their pharmacological effects.

The study of 1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]amino]propan-2-ol exemplifies the beauty of chemistry, where a single compound can lead to a universe of possibilities in medicinal chemistry and beyond. As emphasized by leading scientists, "The future of drug discovery lies in understanding the complexity of every single molecule."


Synonyms
13627-77-5
2680 I.S.
BRN 1385747
alpha-(((2-Hydroxypropyl)amino)methyl)-1,4-benzodioxan-2-methanol
1,4-BENZODIOXAN-2-METHANOL, alpha-(((2-HYDROXYPROPYL)AMINO)METHYL)-
2-(1-Idrossi-2-(beta-idrossipropilammino))etil-1,4-benzodiossano [Italian]
2-(1-Idrossi-2-(beta-idrossipropilammino))etil-1,4-benzodiossano
1-[[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxyethyl]amino]propan-2-ol
alpha-[[(2-Hydroxypropyl)amino]methyl]-1,4-benzodioxane-2-methanol
DTXSID70929310
1-{[2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-2-hydroxyethyl]amino}propan-2-ol