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Tropisetron iodide

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Identification
Molecular formula
C17H25N2O2I
CAS number
105826-92-4
IUPAC name
1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium;iodide
State
State

At room temperature, Tropisetron iodide is generally found in a solid state. The compound is stable under normal conditions and forms crystalline structures.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.00
Boiling point (Celsius)
276.30
Boiling point (Kelvin)
549.30
General information
Molecular weight
408.35g/mol
Molar mass
408.3520g/mol
Density
1.5080g/cm3
Appearence

The compound is typically found as a crystalline solid, often white or off-white in color.

Comment on solubility

Solubility of 1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium;iodide

The solubility of the compound 1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium;iodide is influenced by its unique molecular structure and the presence of the iodide ion. This compound can be categorized based on several factors impacting its solubility:

  • Polarity: The presence of greater polar functional groups, such as the azepan-1-ium moiety, may enhance solubility in polar solvents like water.
  • Ionic Interaction: As an iodide salt, this compound's solubility is often increased in aqueous solutions due to the interaction between the polyatomic ions, favoring dissolution.
  • Hydrophobic Interactions: The benzodioxin moiety can impart some hydrophobic characteristics, potentially reducing solubility in polar solvents.

In summary, the solubility behavior of 1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium;iodide is complex and may vary significantly depending on the solvent used. As noted, “solubility is not merely a function of ionization, it is a delicate balance of structural interactions and environmental conditions.” Exploring the optimal conditions for solubility is essential for practical applications in various fields.

Interesting facts

Interesting Facts about 1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium; iodide

This compound, commonly known for its intricate structure and intriguing properties, is a fascinating representative of the azepan class of quaternary ammonium compounds. Here are several notable aspects:

  • Structural Complexity: The presence of the benzodioxin moiety adds significant structural complexity and potential biological activity to the compound.
  • Pharmaceutical Potential: Compounds with similar structures have been explored for their pharmacological properties, making them of interest to medicinal chemists.
  • Ion Interactions: As an iodide salt, it demonstrates unique interactions with other ions, which can lead to interesting reactivity profiles.
  • Chirality Considerations: The azepan ring can exist in multiple stereochemical configurations, which may influence its reactivity and biological interactions.

Furthermore, it's worth mentioning that the unique alignment of functional groups in this compound can lead to specific binding affinities, a trait that can be crucial in drug design. As noted by researchers, "structure-activity relationship (SAR) studies are essential in understanding how slight modifications to the structure can profoundly affect biological outcomes." This highlights the delicate interplay between chemistry and biological function, particularly in the realm of new therapeutic agents.

In conclusion, 1-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-1-methyl-azepan-1-ium; iodide is not just a simple compound; it's a window into the world of medicinal chemistry, providing insights into how structural variances can lead to varied biological activities. The potential for developing novel therapeutic compounds from its skeleton makes it a rich subject for ongoing research.

Synonyms
2906-84-5
1-(2-(1,4-Benzodioxan-5-yloxy)ethyl)-1-methylhexahydro-1H-azepinium iodide
1H-AZEPINIUM, HEXAHYDRO-1-(2-(1,4-BENZODIOXAN-5-YLOXY)ETHYL)-1-METHYL-, IODIDE
P-20
DTXSID00951664
KAOXMQZGJURCQP-UHFFFAOYSA-M
1-[2-(2,3-dihydro-1,4-benzodioxin-8-yloxy)ethyl]-1-methylazepan-1-iumiodide
1-{2-[(2,3-Dihydro-1,4-benzodioxin-5-yl)oxy]ethyl}-1-methylazepan-1-ium iodide