Interesting facts
Interesting Facts about 1-[2-(2,4-Dichlorophenyl)-2-[(2,6-Dichlorophenyl)methoxy]ethyl]imidazole
This intriguing compound is part of a class of imidazole derivatives which have gained attention in pharmaceutical chemistry for their potential biological activities. Here are some captivating aspects of this compound:
- Pharmaceutical Relevance: Compounds like this imidazole derivative have been studied for their application as antimicrobial agents, anti-inflammatory agents, and potential anticancer therapies. Their unique structure allows them to interact selectively with biological targets.
- Molecular Diversity: The presence of multiple chlorine substituents and methoxy groups in its structure contributes to its pharmacophore, which is crucial for enhancing its activity. This molecular diversity can also affect its interactions with receptors and enzymes.
- Systematic Naming: The systematic name of this compound reflects its complex molecular structure, which provides information about the arrangement of atoms and functional groups, allowing chemists to predict its properties. The name highlights the presence of dichlorophenyl groups and an imidazole ring, underscoring the rich chemistry behind the design of such compounds.
- Research Potential: Several studies have been conducted on related compounds in order to evaluate their effectiveness in treating various diseases. The imidazole ring is known for its ability to participate in essential biological processes, making this compound a candidate for further investigation.
- Structure-Activity Relationship (SAR): Chemists are particularly interested in investigating SAR for this compound as modifications to its structure may significantly enhance its therapeutic efficacy while reducing toxicity, illustrating the delicate balance in drug design.
In summary, 1-[2-(2,4-Dichlorophenyl)-2-[(2,6-Dichlorophenyl)methoxy]ethyl]imidazole offers a fascinating glimpse into the world of medicinal chemistry and the profound impact molecular structure has on biological activity. Its potential continues to inspire research aimed at discovering new therapeutic agents.
Synonyms
Isoconazole
27523-40-6
Isoconazol
Isoconazolum
Travogen
Isoconazol [INN-Spanish]
Isoconazolum [INN-Latin]
1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole
EINECS 248-508-3
GRI7WFR424
Isoconazole [USAN:INN:BAN]
MICONAZOLE 2,6-ISOMER
DTXSID7045447
ISOCONAZOLE [MI]
ISOCONAZOLE [USAN]
ISOCONAZOLE [MART.]
ISOCONAZOLE [WHO-DD]
R-15,454 [AS NITRATE SALT]
R15454 FREE BASE
DTXCID5025447
R-15454 FREE BASE
CHEBI:83667
ISOCONAZOLE [EP IMPURITY]
ISOCONAZOLE [EP MONOGRAPH]
1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)1H-imidazole
1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)-
MICONAZOLE IMPURITY D [EP IMPURITY]
Imidazole, 1-(2,4-dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)-
Isoconazol (INN-Spanish)
Isoconazolum (INN-Latin)
1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole
ISOCONAZOLE (MART.)
MICONAZOLE NITRATE IMPURITY D [EP IMPURITY]
ISOCONAZOLE (EP IMPURITY)
ISOCONAZOLE (EP MONOGRAPH)
1-[2,4-dichloro-beta-[(2,6-dichlorobenzyl)oxy]phenethyl]imidazole
1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-
R-15,454 (AS NITRATE SALT)
MICONAZOLE IMPURITY D (EP IMPURITY)
Miconazole Impurity D
MICONAZOLE NITRATE IMPURITY D (EP IMPURITY)
UNII-GRI7WFR424
isoconazolo
rac-isoconazole
1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
1-(2-((2,6-DICHLOROBENZYL)OXY)-2-(2,4-DICHLOROPHENYL)ETHYL)-1H-IMIDAZOLE
rac-1-(2-((2,6-dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
racemic isoconazole
(RS)-isoconazole
NCGC00016800-01
Imidazole, 1-[2,4-dichloro-ss-[(2,6-dichlorobenzyl)oxy]phenethyl]- (8CI); 1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; (+/-)-Isconazole; Isoconazole
Prestwick_532
(+-)-isoconazole
CAS-27523-40-6
1-(2,4-dichloro beta-(2,6-dichlorobenzyloxy)phenethyl) imidazole
Prestwick0_000127
Prestwick1_000127
Prestwick2_000127
Prestwick3_000127
Isoconazole (USAN/INN)
cid_3760
BSPBio_000174
MLS002154207
SCHEMBL148288
SPBio_002113
BPBio1_000192
CHEMBL1571863
BDBM31771
CHEBI:82865
D01AC05
G01AF07
HMS1568I16
HMS2095I16
HMS2231P05
HMS3374M05
HMS3712I16
Tox21_110616
AKOS015896434
Tox21_110616_1
CCG-220127
DB08943
NCGC00179642-01
NCGC00179642-02
NCGC00179642-03
NCGC00179642-04
NCGC00179642-05
FI137461
SMR001233493
NS00006034
D04624
EN300-18563488
Q262210
SR-01000838847
SR-01000838847-2
BRD-A93353767-001-03-5
BRD-A93353767-008-02-2
1-(2-(2,6-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
1-[2,4-Dichloro-.beta.-[2,6-dichlorobenzyl)oxy]phenylethyl]imidazole
1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}imidazole
1-(2,4-DICHLORO-.BETA.-((2,6-DICHLOROBENZYL)OXY)PHENETHYL)IMIDAZOLE
Imidazole, 1-(2,4-dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)-(8CI)
248-508-3
Solubility of 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole (C18H14Cl4N2O)
The solubility of 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole is influenced by its complex molecular structure, which includes multiple chlorine substituents and an imidazole ring.
Factors Affecting Solubility
However, due to the halogenated nature of the compound and its overall size, the solubility is expected to be limited in water while potentially better in organic solvents such as ethanol or acetone.
In practical terms, it is pivotal to test the solubility under different conditions to ascertain its behavior effectively. As is often stated in chemistry, “The solubility of a compound largely dictates its usability in various applications.” Therefore, understanding the solubility characteristics of this compound is essential for its practical applications.