Skip to main content

Tetrabenazine

ADVERTISEMENT
Identification
Molecular formula
C19H22Cl3NO4
CAS number
102601-59-6
IUPAC name
1-[2-(3,4-dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

The compound is typically a solid at room temperature.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
318.90
Boiling point (Kelvin)
592.05
General information
Molecular weight
375.25g/mol
Molar mass
375.2460g/mol
Density
1.3000g/cm3
Appearence

This compound typically appears as a white to slightly yellow crystalline powder. It is important to store it in a controlled environment to maintain its stability and prevent degradation.

Comment on solubility

Solubility of 1-[2-(3,4-dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride

The solubility of the compound 1-[2-(3,4-dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride is an intriguing area of study, especially considering its complex structure. Here are some key points to note regarding its solubility:

  • Solvent Dependence: This compound is likely to exhibit different solubility characteristics depending on the solvent used. For instance, it may be more soluble in polar solvents such as water and methanol due to the presence of the cationic +1 charge and polar functional groups.
  • pH Sensitivity: The solubility could also be affected by the pH of the solution. In acidic conditions, the ionic form may be stabilized, thereby enhancing solubility.
  • Hydrophobic Interactions: The presence of multiple aromatic rings and methoxy groups may lead to hydrophobic interactions that could inhibit solubility in non-polar solvents.

As noted in various studies, "The solubility of complex organic compounds can often be optimized through careful selection of appropriate solvents and conditions." Thus, understanding the specific interactions within this compound is essential for predicting its solubility behavior accurately.

In summary, exploring the solubility of this compound not only highlights the interplay of structural features but also emphasizes the important role played by environmental factors in solubility science.

Interesting facts

Interesting Facts about 1-[2-(3,4-Dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride

The compound 1-[2-(3,4-dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride belongs to an intriguing class of molecules known as isoquinolines. These compounds are noted for their vast range of biological activities, making them of great interest in medicinal chemistry.

Key Characteristics

  • Isoquinoline Framework: The isoquinoline structure is foundational in numerous pharmacological agents, contributing to their efficacy in treating various diseases.
  • Sulfinyl Group: The presence of a sulfinyl group in this compound can enhance its reactivity, potentially leading to unique interactions in biological systems.
  • Chlorinated Phenyl Ring: The dichlorophenyl moiety significantly impacts the compound's electronic properties, which may influence its interaction with biological targets.

This compound is especially noteworthy due to its potential as a therapeutic agent. Researchers are exploring its application in treating conditions related to:

  • Cancer: The bioactivity associated with isoquinolines could be pivotal in developing anti-cancer drugs.
  • Nervous System Disorders: Compounds with similar structures have shown promises as neuroprotective agents.
  • Inflammatory Diseases: Potential anti-inflammatory properties open avenues for managing chronic conditions.

Moreover, the compound’s unique functional groups afford opportunities for further modifications, leading to new derivatives with possibly enhanced therapeutic profiles. As stated by researchers, “The importance of structural diversity in drug design cannot be overstated, as it allows for the honing of specific activities while minimizing side effects.”

In summary, 1-[2-(3,4-dichlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride exemplifies the intricate relationship between chemical structure and biological activity, reinforcing the exciting potential of isoquinoline derivatives in modern drug discovery.

Synonyms
22336-78-3
Isoquinoline, 1-(2-((3,4-dichlorophenyl)sulfinyl)ethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, hydrochloride
RefChem:349968