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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine
State
State

At room temperature, venlafaxine is typically found in a solid-state. It is most often seen in pharmaceutical settings as a prepared dosage form such as tablets or capsules meant for oral administration.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
465.90
Boiling point (Kelvin)
739.10
General information
Molecular weight
313.87g/mol
Molar mass
313.8650g/mol
Density
1.2730g/cm3
Appearence

Venlafaxine appears as a white to off-white crystalline solid. It is slightly soluble in water and freely soluble in methanol. This compound is commonly formulated in various pharmaceutical preparations, appearing as tablets and capsules.

Comment on solubility

Solubility of 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine

The solubility of 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine is influenced by several factors including its molecular structure and the presence of various functional groups. This compound features a complex molecular architecture, which can significantly affect its interaction with solvents. Here are some key considerations:

  • Polarity: Due to the presence of both hydrophobic (phenyl and methoxy groups) and hydrophilic (nitro group) components, its solubility might vary in different solvents. Generally, it is expected to have limited solubility in water but could be more soluble in organic solvents such as ethanol and dimethyl sulfoxide.
  • Hydrogen Bonding: The potential for hydrogen bonding may arise from the nitro group, which could enhance solubility in polar solvents.
  • Thermodynamic Factors: Entropy and enthalpy changes during dissolution play a critical role, where the energy required to overcome intermolecular forces within the compound and that of solvent molecules come into play.

To summarize, while it is challenging to predict the exact solubility without experimental data, the structure of 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine suggests limited solubility in water and possibly better solubility in non-polar or polar organic solvents. Thus, careful consideration must be taken when evaluating its use in various applications where solubility is a crucial factor.

Interesting facts

Interesting Facts about 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine

This complex organic compound, known as 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine, represents a fascinating intersection between medicinal chemistry and organic synthesis. Here are some remarkable insights about this compound:

  • Structure and Design: The intricate structure includes multiple functional groups that enhance its reactivity and biological activity. The presence of the pyrrolidine ring contributes to its potential as a pharmaceutical agent, while the nitro and methoxy groups significantly influence its electronic properties.
  • Biological Activity: Compounds similar to this one have shown promising results in various studies related to drug discovery, particularly in targeting neurological and cancer-related pathways. Researchers are continually exploring its potential therapeutic roles.
  • Multifunctionality: The unique combination of the vinyl and phenoxy groups suggests potential applications in fields beyond medicinal chemistry, such as polymer science and materials chemistry, which is vital for developing new materials with specific properties.
  • Synthetic Challenges: The synthesis of this compound is not trivial, often requiring advanced techniques in organic chemistry. Its preparation may involve several steps, including condensation reactions and functional group transformations.

As researchers delve deeper into compounds like 1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenyl-vinyl]phenoxy]ethyl]pyrrolidine, they unlock new possibilities in the world of pharmaceuticals and materials science. This compound represents an exciting area of study that bridges fundamental science with real-world applications.

Synonyms
NITROMIFENE
Nitromifeno
Nitromifene [INN]
5FS1NJ6Q8N
CI 628
Nitromifenum
1-(2-(P-(.ALPHA.-(P-METHOXYPHENYL)-.BETA.-NITROSTYRYL)PHENOXY)ETHYL)PYRROLIDINE
Nitromifenum (INN-Latin)
Nitromifenum [INN-Latin]
Nitromifeno (INN-Spanish)
Nitromifeno [INN-Spanish]
DTXSID50883143
Nitromiphene
CN 55945
AI3-51875
CN-55,945
CN-55945-27
1-(2-(p-(alpha-(p-Methoxyphenyl)-beta-nitrostyryl)phenoxy)ethyl)pyrrolidine
Pyrrolidine, 1-(2-(p-(alpha-(p-methoxyphenyl)-beta-nitrostyryl)phenoxy)ethyl)-
DTXCID401842049
1-[2-[4-[1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine
UNII-5FS1NJ6Q8N
CI628
CHEMBL4594228
DTXSID10864271
KAA44884
Q27262013
1-(2-{4-[(E)-1-(4-Methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy}ethyl)pyrrolidine