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Bazedoxifene

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Identification
Molecular formula
C30H34N2O3S
CAS number
198481-32-2
IUPAC name
1-[2-[4-[[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]benzothiophen-3-yl]methyl]phenoxy]ethyl]pyrrolidine
State
State

At room temperature, Bazedoxifene is a solid compound typically found in powder form.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
767.80
Boiling point (Kelvin)
1 040.95
General information
Molecular weight
470.68g/mol
Molar mass
470.6310g/mol
Density
1.2800g/cm3
Appearence

Bazedoxifene is a white to off-white powder.

Comment on solubility

Solubility of 1-[2-[4-[[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]benzothiophen-3-yl]methyl]phenoxy]ethyl]pyrrolidine

The solubility of the compound C30H34N2O3S can exhibit intriguing characteristics due to its structural complexity. As a large organic molecule with multiple functional groups, its solubility is greatly influenced by the following factors:

  • Polarity: The presence of polar functional groups such as -O- (ether) and -N- (amine) can enhance solubility in polar solvents like water.
  • Molecular Size: Being a high molecular weight compound, solubility in polar solvents may be limited compared to smaller organic compounds.
  • Hydrophobic Regions: The existence of large aromatic rings and aliphatic segments may favor solubility in non-polar solvents like dichloromethane or ethyl acetate.
  • Temperature Dependency: Solubility can often increase with temperature, making it essential to consider thermal conditions when assessing solubility.

In general, it can be said that:

  1. If dissolved in polar solvents, you may observe partial solubility.
  2. In non-polar solvents, the compound is likely to exhibit better solubility.

As with many complex organic compounds, determining the precise solubility requires experimental evaluation, and the solubility behavior can be summarized as a balance between polar and non-polar interactions.

Interesting facts

Exploring 1-[2-[4-[[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]benzothiophen-3-yl]methyl]phenoxy]ethyl]pyrrolidine

This intriguing compound, commonly referred to as a complex pharmacological agent, showcases the fascinating interplay of structure and function in medicinal chemistry. Known for its multifaceted chemical architecture, it combines the efficacy of pyrrolidine and benzothiophene to create a robust therapeutic candidate.

Key Insights:

  • Diverse Applications: This compound is being studied for its potential use in treating various neurological disorders. Its unique structure allows for interactions with biological pathways that are crucial in drug development.
  • Design Inspiration: The molecule is designed using fragments from different biological scaffolds, making it a prime example of structure-activity relationship (SAR) analysis in drug discovery.
  • Pharmacophore Features: The presence of key functional groups significantly enhances its binding affinity to target receptors, a vital aspect for any therapeutic agent.
  • Synthetic Challenge: The synthesis of such a complex compound poses significant challenges, often requiring advanced techniques in organic synthesis and purification.

The exploration of 1-[2-[4-[[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]benzothiophen-3-yl]methyl]phenoxy]ethyl]pyrrolidine highlights the continuous advancements in medicinal chemistry and the endless possibilities in designing compounds with specific therapeutic effects. As researchers delve deeper into its properties, we anticipate exciting breakthroughs that could potentially transform treatment paradigms.

Synonyms
3-[4-(2-pyrrolidin-1-yl-ethoxy)-benzyl]-2-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl] -benzo[b]thiophene
1d3q
CHEMBL77366
SCHEMBL6596926
Q27458539
1-(2-(4-(3-(4-(2-(Pyrrolidin-1-yl)ethoxy)benzyl)benzo[b]thiophen-2-yl)phenoxy)ethyl)pyrrolidine
1-[2-(4-{3-[4-(2-pyrrolidin-1-ylethoxy)benzyl]-1-benzothiophen-2-yl}phenoxy)ethyl]pyrrolidine
193960-57-5