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Chlorphenoxamine

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Identification
Molecular formula
C19H23ClN2O
CAS number
77-38-3
IUPAC name
1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine
State
State

The compound is typically in a solid state at room temperature.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.15
Boiling point (Celsius)
128.00
Boiling point (Kelvin)
401.15
General information
Molecular weight
306.85g/mol
Molar mass
306.8200g/mol
Density
0.9830g/cm3
Appearence

The compound typically presents as a white crystalline solid.

Comment on solubility

Solubility of 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine

1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine is an intriguing compound with notable solubility characteristics that are influenced by its molecular structure and functional groups. When examining its solubility, several key factors come into play:

  • Polar vs. Nonpolar Traits: The presence of the methoxy group and the aromatic rings contribute both polar and nonpolar characteristics, potentially leading to varied solubility in different solvents.
  • Solvent Interaction: This compound may exhibit good solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), while its solubility in water could be significantly lower due to the bulky aromatic portions of the molecule.
  • Hydrogen Bonding: The availability of hydroxyl groups (when considering the entirety of its structural analogs) can enhance solubility in polar solvents through hydrogen bonding patterns.

In summary, the solubility of 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine can be classified as:

  1. Moderately Soluble: In organic solvents
  2. Poorly Soluble: In aqueous solutions

This compound's unique structural features illustrate how chemical properties significantly affect solubility profiles in various mediums.

Interesting facts

Exciting Insights on 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine

1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine is a fascinating compound that belongs to the class of piperazines, which are heterocyclic compounds containing a six-membered ring with two nitrogen atoms. Here are some notable aspects of this compound that highlight its importance in the field of chemistry:

  • Pharmaceutical Applications: Due to its complex structure, this compound is of interest for its potential pharmaceutical applications. It may act on various neurotransmitter systems, making it a candidate for research in treating psychiatric disorders.
  • Structure-Activity Relationship (SAR): The compound's unique arrangement of a methoxy group and a chlorophenyl moiety provides ample opportunities for SAR studies. Understanding how variations in the structure influence biological activity can lead to more effective drug design.
  • Research Activity: Compounds like this one are often studied for their antipsychotic and antidepressant effects. Their intricate designs can lead to new findings in behavioral pharmacology.
  • Synthetic Pathways: The synthesis of this compound involves multi-step organic reactions, often including methods such as nucleophilic substitution and aromatic coupling, which are essential techniques in medicinal chemistry.

As noted by experts in the field, "the design of new pharmacological agents necessitates a deep understanding of not just the molecules themselves, but also their interactions with biological systems." This compound serves as an excellent case study in such research endeavors.

In summary, 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]-4-methyl-piperazine stands as a testament to the intricate balance of chemistry and pharmacology, making it a compound worthy of research and exploration.

Synonyms
AET2OMT56X
UNII-AET2OMT56X
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)-4-methylpiperazine
94910-45-9
Piperazine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-4-methyl-
1-(2-(p-Chloro-alpha-phenylbenzyloxy)ethyl)-4-methylpiperazine
1-(2-(P-CHLORO-.ALPHA.-PHENYLBENZYLOXY)ETHYL)-4-METHYLPIPERAZINE