Interesting facts
Interesting Facts About 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine
This compound, 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine, is an intriguing member of the piperidine family, well-known for its diverse applications in medicinal chemistry. Here are some captivating aspects of this compound:
- Pharmacological Interest: Compounds like this one are often evaluated in drug discovery for their potential as therapeutic agents, particularly in the treatment of neurological disorders and pain management.
- Chlorine Substituent: The presence of the chlorophenyl group enhances the compound's lipophilicity, which can be crucial for its ability to cross the blood-brain barrier, a key factor in central nervous system pharmacology.
- Structural Versatility: The combination of a piperidine ring with various substituents allows for a wide range of structural modifications, offering chemists the opportunity to optimize pharmacological properties.
- Mechanism of Action: Compounds of this type may interact with neurotransmitter systems, particularly those involving serotonin and dopamine, which are critical in regulating mood and cognition.
- Research Applications: Beyond medicine, this compound may find utility in studies focusing on chemical reactions involving heterocycles, as well as in synthesis pathways involving piperidine derivatives.
In summary, 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine serves as a fascinating example of how chemical design and structure can impact biological activity, paving the way for innovations in pharmaceuticals and beyond.
Synonyms
cloperastine
3703-76-2
Cloperastina
Cloperastine [INN]
Cloperastinum
1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine
1-(2-((4-chlorophenyl)(phenyl)methoxy)ethyl)piperidine
EINECS 223-042-3
Cloperastinum [INN-Latin]
HT-11
Cloperastina [INN-Spanish]
UNII-69M5L7BXEK
69M5L7BXEK
BRN 0275589
Cloperastine (INN)
Piperidine, 1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]-
CLOPERASTINE [MI]
NSC-758635
CLOPERASTINE [MART.]
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
CLOPERASTINE [WHO-DD]
Piperidine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-
DTXSID7048532
Cloperastine (hydrochloride)
5-20-02-00105 (Beilstein Handbook Reference)
NSC 758635
1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine
Piperidine, 1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-
Cloperastinum (INN-Latin)
Cloperastina (INN-Spanish)
CLOPERASTINE (MART.)
1-{2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl}piperidine
LevocloperastineIH
1-(2-[(p-Chloro-.alpha.-phenylbenzyl)oxy]ethyl)piperidine
Piperidine, 1-(2-((p-chloro-.alpha.-phenylbenzyl)oxy)ethyl)-
1-(2-((P-CHLORO-.ALPHA.-PHENYLBENZYL)OXY)ETHYL)PIPERIDINE
HT 11
1-(2-((P-CHLORO-ALPHA-PHENYLBENZYL)OXY)ETHYL)PIPERIDINE
cloperastine-fendizoate
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine
Spectrum_001570
Prestwick0_000793
Prestwick1_000793
Prestwick2_000793
Prestwick3_000793
Spectrum2_001596
Spectrum3_001895
Spectrum4_000844
Spectrum5_001448
BSPBio_000926
BSPBio_003430
KBioGR_001447
KBioSS_002050
DivK1c_000840
SCHEMBL284715
SPBio_001592
SPBio_002865
BPBio1_001020
CHEMBL415087
1- 2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl piperidine
DTXCID4027999
CHEBI:94448
KBio1_000840
KBio2_002050
KBio2_004618
KBio2_007186
KBio3_002933
R05DB21
NINDS_000840
HFA30191
BDBM50237287
STK646871
AKOS005577799
DB09002
FC76634
IDI1_000840
NCGC00178069-01
NCGC00178069-02
NCGC00178069-03
SBI-0051861.P002
AB00053681
VU0244436-2
D03557
AB00053681_08
EN300-18567806
Q2055825
BRD-A80908310-003-05-4
BRD-A80908310-003-08-8
BRD-A80908310-003-13-8
1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine
1-(2-[(4-Chlorophenyl)(phenyl)methoxy]ethyl)piperidine #
Piperidine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-(9CI)
223-042-3
Solubility of 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine (C16H22ClNO)
The solubility of 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine in various solvents is a significant aspect to consider when examining its chemical properties. This compound, bearing both hydrophobic and hydrophilic characteristics, demonstrates variable solubility:
It is essential to remember that factors influencing solubility include:
In conclusion, while it is unlikely to dissolve significantly in aqueous environments, 1-[2-[(4-chlorophenyl)-phenyl-methoxy]ethyl]piperidine shows improved solubility in various organic solvents, making it versatile for certain applications. Always consider the specific solvent and environmental conditions when assessing solubility.