Modafinil | Solubility of Things

Identification

Molecular formula

C₁₅H₁₅ClNO₂S

CAS number

68693-11-8

IUPAC name

1-[2-(4-chlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

State

At room temperature, Modafinil is typically in a solid-state.

Melting point (Celsius)

164.00

Melting point (Kelvin)

437.15

Boiling point (Celsius)

629.40

Boiling point (Kelvin)

902.40

General information

Molecular weight

273.35g/mol

Molar mass

273.3490g/mol

Density

1.2994g/cm³

Appearence

Modafinil is generally a white to off-white, crystalline powder.

Comment on solubility

Solubility of 1-[2-(4-chlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

The solubility of 1-[2-(4-chlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline can be influenced by several key factors, including its molecular structure and the presence of specific functional groups. Here are some important points to consider:

Polarity: The presence of sulfinyl and methoxy groups indicates some level of polarity, which may enhance solubility in polar solvents.
Solvent Compatibility: This compound may exhibit differential solubility in various solvents, including water, ethanol, or other organic solvents.
Temperature Effects: As with many compounds, solubility may increase with temperature, making heating a useful technique for dissolving this compound if it is insoluble at room temperature.
Concentration Dependencies: Saturation concentrations can provide insight into solubility limits and related applications.

In conclusion, it is essential to conduct empirical studies to accurately determine the solubility characteristics of this compound in different solvents, as theoretical predictions based on its structure may not always align with practical observations. Ultimately, understanding its solubility will facilitate better utilization in various chemical and pharmaceutical applications.

Interesting facts

Interesting Facts about 1-[2-(4-chlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

This compound is a fascinating member of the isoquinoline family, a group known for their diverse biological activities. Here are some intriguing aspects worth noting:

Structural Diversity: Isoquinolines, like this compound, exhibit a complex molecular architecture that contributes to varied pharmacological properties. The presence of a sulfinyl group and multiple methoxy functionalities enriches its chemical landscape.
Biological Relevance: Compounds with similar structures are often investigated for potential medicinal properties. They can exhibit antidepressant, antitumor, and analgesic effects, making them valuable in pharmaceutical research.
Chirality Matters: The inherent chirality in such compounds may lead to enantiomers that could possess differing activities, emphasizing the importance of stereoisomerism in drug efficacy and safety.
Phenyl Ring Influence: The incorporation of a chlorophenyl group in the structure can significantly influence the interaction with biological targets, enhancing binding affinity or selectivity.
Research Potential: The unique characteristics of this compound offer immense opportunities for synthetic chemists and pharmacologists alike. Ongoing research may unveil new applications or therapeutic avenues.

In conclusion, 1-[2-(4-chlorophenyl)sulfinylethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline stands as a prime example of how intricate chemical structures can lead to promising biological insights and therapeutic possibilities. Its study can pave the way for innovative drug discovery.