No common name | Solubility of Things

Identification

Molecular formula

C₂₂H₂₀ClN₃O₄

CAS number

135575-42-7

IUPAC name

1-[2-[(5-chloro-1H-indole-2-carbonyl)amino]-3-phenyl-propanoyl]azetidine-3-carboxylic acid

State

Solid at room temperature, typically in a crystalline powder form.

Melting point (Celsius)

214.70

Melting point (Kelvin)

487.90

Boiling point (Celsius)

278.60

Boiling point (Kelvin)

551.80

General information

Molecular weight

436.88g/mol

Molar mass

436.8790g/mol

Density

1.3600g/cm³

Appearence

The compound is typically a solid with a crystalline appearance. The presence of the indole and phenyl groups may impart some yellowish tint but the exact appearance can depend on the purity and form of the sample.

Comment on solubility

Solubility of 1-[2-[(5-chloro-1H-indole-2-carbonyl)amino]-3-phenyl-propanoyl]azetidine-3-carboxylic acid

The solubility of 1-[2-[(5-chloro-1H-indole-2-carbonyl)amino]-3-phenyl-propanoyl]azetidine-3-carboxylic acid (C₂₂H₂₀ClN₃O₄) can be characterized by several factors:

Polarity: The presence of polar functional groups, such as carboxylic acids and amine groups, generally enhances solubility in polar solvents like water. However, the hydrophobic indole and phenyl groups can hinder its overall solubility.
Solvent Interaction: This compound may exhibit better solubility in organic solvents or mixed-solvent systems where hydrogen bonding and van der Waals interactions play a crucial role.
pH Dependency: The solubility might vary with pH, particularly due to the ionizable carboxylic acid group, which could lead to increased solubility in alkaline conditions as it gets deprotonated.
Temperature Influence: Increased temperature often enhances the solubility of solids in liquid solvents, which could be a factor to consider when studying this compound's solubility profile.

In summary, understanding the solubility of this compound is essential for its applications in pharmaceuticals and materials science. Experimentation with various solvents, pH levels, and temperatures could provide deeper insights into its solubility behavior. Note that quantitative solubility data should be derived from empirical studies to facilitate practical applications.

Interesting facts

Interesting Facts about 1-[2-[(5-chloro-1H-indole-2-carbonyl)amino]-3-phenyl-propanoyl]azetidine-3-carboxylic acid

This compound is a remarkable example of the interplay between heterocyclic compounds and amino acids, showcasing the creativity found in medicinal chemistry. Here are some intriguing facts:

Innovative Structure: The compound features an azetidine ring, which is a four-membered cyclic amine known for its unique properties. The incorporation of this ring can lead to novel pharmacological activities.
Indole Moiety: The presence of the indole structure is significant as indoles are well-known for their role in various biological processes. They are often found in numerous natural compounds and drugs, demonstrating vital properties such as anti-inflammatory and anticancer activities.
Chlorine Substitution: The chlorine atom in the structure may enhance the compound's bioactivity. Chlorinated compounds frequently exhibit increased hydrophobicity, which can influence their interactions with biological targets.
Potential Therapeutic Applications: Given its structure, this compound could be designed for use in pharmaceuticals targeting specific biological pathways, particularly in cancer research or other therapeutic areas involving indole derivatives.
Peptide Bonds: The presence of an amide bond denotes peptide-like characteristics, which is crucial for maintaining biological activity. It may facilitate interactions with various biological macromolecules such as proteins and enzymes.

As a potential candidate for drug development, this compound exemplifies the importance of structural diversity in creating molecules that can target specific biological pathways. Continued investigation into its properties may reveal more about its potential medicinal applications.

Synonyms

SCHEMBL4321353

PD041093