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2-Acetoanilide

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Identification
Molecular formula
C8H9NO
CAS number
551-93-9
IUPAC name
1-(2-aminophenyl)ethanone
State
State

At room temperature, 2-Acetoanilide is a solid. It appears as off-white to light yellow crystalline solids that are stable under regular conditions.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.00
Boiling point (Celsius)
278.00
Boiling point (Kelvin)
551.00
General information
Molecular weight
135.17g/mol
Molar mass
135.1660g/mol
Density
1.1220g/cm3
Appearence

2-Acetoanilide is typically found as a crystalline solid. The crystals are often off-white to light yellow.

Comment on solubility

Solubility of 1-(2-aminophenyl)ethanone

The solubility of 1-(2-aminophenyl)ethanone, a compound with the chemical formula C8H9NO, can be described through a few key points:

  • Polarity: This compound contains both an amino group and a carbonyl group, which introduces polarity, allowing it to interact with polar solvents.
  • Solvent Compatibility: 1-(2-aminophenyl)ethanone is expected to be more soluble in:
    • Polar solvents like water and alcohols.
    • Organic solvents such as ethanol and methanol.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature. This allows for better dissolution in warm solvent conditions.
  • Potential Limitations: While it may be soluble in polar solvents, the presence of hydrophobic aryl groups could limit solubility in more non-polar environments, such as hydrocarbons.

Overall, it’s fair to say that 1-(2-aminophenyl)ethanone exhibits moderate solubility characteristics, heavily influenced by its functional groups and the nature of the solvent used. As a quotable insight, it can be said that “solubility is a reflection of molecular interactions” which accurately emphasizes the interplay between structure and solvent choice.

Interesting facts

Exploring 1-(2-aminophenyl)ethanone

1-(2-aminophenyl)ethanone, also known as 2'-Aminoacetophenone, is an intriguing organic compound with a variety of applications in both industrial and research settings. Below are some interesting facts that highlight its significance:

  • Versatile Intermediate: This compound serves as a crucial intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes, showcasing its diverse utility in chemical manufacturing.
  • Biological Activity: Studies have shown that 1-(2-aminophenyl)ethanone exhibits noteworthy biological properties, including antimicrobial and antioxidant activities, making it a subject of interest for drug development.
  • Synthetic Routes: The compound can be synthesized through various methods, including reaction of 2-aminophenol with acetic anhydride, demonstrating the versatility of organic synthesis techniques.
  • Indicator in Research: It has been utilized as a probe for studying enzyme activity in biochemical research, offering insights into metabolic processes.
  • Impact on Material Science: Its derivatives are explored for applications in making resins and other materials, indicating its significance beyond just pharmaceuticals.

As a scientist or chemistry student, understanding the properties and applications of 1-(2-aminophenyl)ethanone not only broadens your chemical knowledge but also provides a window into the intersection of chemistry with biology and material science. In the words of chemists, “Every compound has a story to tell; it’s our job to listen.”


Synonyms
2'-Aminoacetophenone
551-93-9
1-(2-Aminophenyl)ethanone
O-AMINOACETOPHENONE
2-Acetylaniline
o-Acetylaniline
o-Aminoacetylbenzene
1-Acetyl-2-aminobenzene
Acetophenone, 2'-amino-
Ethanone, 1-(2-aminophenyl)-
1-(2-Aminophenyl)Ethan-1-One
ortho-aminoacetophenone
2'-Amonioacetophenone
2-acetylphenylamine
o-Aminophenyl methyl ketone
NSC 8820
5 kaal
DTXSID4052213
HSDB 5494
NSC-8820
EINECS 209-002-8
69Y77091BC
AI3-04095
DTXCID6030784
FEMA NO. 3906
CHEBI:91110
O-AMINOACETOPHENONE [HSDB]
2'-AMINOACETOPHENONE [FHFI]
oAcetylaniline
2Acetylaniline
2aminoacetophenone
2-acetyl aniline
oAminoacetylbenzene
1Acetyl2aminobenzene
2'Amonioacetophenone
Acetophenone, 2'amino
Ethanone, 1(2aminophenyl)
Acetophenone, 2'-amino-(8CI)
209-002-8
1-(2-aminophenyl)-ethanone
MFCD00007717
1-(2-amino-phenyl)-ethanone
125507-96-2
Ethanol, 1-(6-imino-2,4-cyclohexadien-1-ylidene)- (9CI)
27941-88-4
2'-Aminoacetophenone, >=98%
Ethanone, 1-(aminophenyl)-
UNII-69Y77091BC
6-acetyl-aniline
o-Amino acetophenone
orthoaminoacetophenone
2`-Aminoacetophenone
aniline, 2-acetyl-
1-acetyl-aminobenzene
2'-Amino acetophenone
1-(Aminophenyl)-Ethanone
1-(2'-aminophenyl)ethanone
2'-Aminoacetophenone, 98%
SCHEMBL309044
2-(methylcarbonyl)benzeneamine
1-(2-Aminophenyl)ethanone #
1-(2-aminophenyl)-1-ethanone
CHEMBL2251601
1-(2-aminophenyl)ethane-1-one
2'-Aminoacetophenone (Standard)
FEMA 3906
GTDQGKWDWVUKTI-UHFFFAOYSA-
HY-I0501R
NSC8820
1-(2-Aminophenyl)ethanone, 9CI
CS-D1191
HY-I0501
STR00923
Tox21_304027
STL146696
AKOS000120944
FA37100
PS-4579
NCGC00357236-01
2'-Aminoacetophenone, analytical standard
AC-25881
BP-21338
CAS-551-93-9
SY001368
DB-014028
DB-275746
A0250
A7989
NS00022361
2 inverted exclamation mark -Aminoacetophenone
EN300-18094
Q27163057
ETHANOL, 1-(6-IMINO-2,4-CYCLOHEXADIEN-1-YLIDENE)-
InChI=1/C8H9NO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,9H2,1H3
VNJ