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Tamoxifen

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Identification
Molecular formula
C26H29NO
CAS number
10540-29-1
IUPAC name
1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene
State
State

At room temperature, Tamoxifen is in a solid state as a white crystalline powder. It is not volatile and maintains a stable form unless subjected to high temperatures.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
147.50
Boiling point (Kelvin)
420.65
General information
Molecular weight
371.83g/mol
Molar mass
371.8300g/mol
Density
1.1257g/cm3
Appearence

Tamoxifen typically appears as a white crystalline solid that is odorless. These crystals are often fine, and the compound is known for its stability under normal conditions.

Comment on solubility

Solubility of 1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene

The solubility of the compound 1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene is influenced by its unique structural characteristics. Given its complex molecular structure, several factors dictate its solubility behavior:

  • Polarity: This compound has a mix of polar and nonpolar regions. The presence of the -OCH3 (methoxy) group can contribute to some polarity, while the aromatic rings are generally hydrophobic.
  • Hydrogen Bonding: The methoxy group may engage in hydrogen bonding with polar solvents, enhancing solubility in some organic solvents.
  • Solvent Type: The solubility is likely to be higher in organic solvents such as ethanol or acetone compared to water, due to the hydrophobic nature of the aromatic components.

In summary, the solubility of 1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene can be described as moderate in polar organic solvents while being significantly less soluble in water. As a result, this compound exemplifies the general principle that "like dissolves like," where solvent polarity plays a crucial role in solubility dynamics.

Interesting facts

Interesting Facts about 1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene

This compound is an intriguing example of complex organic chemistry, showcasing the beauty of substituted aromatic systems. Here are some fascinating insights about it:

  • Dual Functionality: The presence of both bromine and chlorine substituents indicates that this compound might possess unique chemical reactivity patterns, potentially making it useful in various reactions such as nucleophilic substitution or coupling reactions.
  • Application in Material Science: Compounds like this one can play a significant role in the development of organic electronic materials, particularly in applications like organic light-emitting diodes (OLEDs) and solar cells due to their electronic properties.
  • Relevance in Medicinal Chemistry: The methoxy group introduces interesting electron-donating properties that can enhance biological activity. Such compounds are often explored for their potential therapeutic applications, for example, as anti-inflammatory or anti-cancer agents.
  • Synthetic Pathways: The synthetic route to obtain this compound may involve various methods, including cross-coupling reactions such as the Suzuki or Heck reactions, demonstrating the versatility of modern organic synthesis.
  • Zone of Interest: The compound falls into the category of vinyl-aryl compounds, which has sparked interest in polymer chemistry for developing new materials with specific physical properties.

In summary, 1-[2-bromo-2-(4-chlorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene is more than just a mere molecular structure; it embodies the depth of chemical interactions and the potential for innovative applications in various scientific fields. As we explore this compound, we uncover not just its chemical nature but its potential impact on technology and health.