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Tamoxifen

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Identification
Molecular formula
C26H29NO4S
CAS number
10540-29-1
IUPAC name
1-[2-bromo-2-(4-fluorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene
State
State

At room temperature, Tamoxifen is typically a solid.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
537.00
Boiling point (Kelvin)
810.00
General information
Molecular weight
563.05g/mol
Molar mass
563.0460g/mol
Density
1.1147g/cm3
Appearence

Tamoxifen appears as a white crystalline solid. It is often odorless and can have a powdery texture.

Comment on solubility

Solubility of 1-[2-bromo-2-(4-fluorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene

The solubility of 1-[2-bromo-2-(4-fluorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene can be described as follows:

  • Hydrophobic Character: This compound contains multiple aromatic rings, which typically contribute to hydrophobicity. Consequently, it is less likely to dissolve in polar solvents.
  • Solvent Compatibility: It may exhibit better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or acetone when compared to water due to its non-polar similarities.
  • Impact of Substituents: The presence of both the bromo and methoxy substituents affects solubility. For instance, the bromo group can introduce some polar characteristics, potentially enhancing solubility in certain mixed solvents.

In summary, while predictions about solubility should always be confirmed through experimental data, one can expect that 1-[2-bromo-2-(4-fluorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene will be more soluble in non-polar or slightly polar solvents than in highly polar solvents. As always, laboratory testing is essential to determine the precise solubility behavior of this compound.

Interesting facts

Interesting Facts About 1-[2-Bromo-2-(4-Fluorophenyl)-1-Phenyl-Vinyl]-4-Methoxy-Benzene

This intriguing organic compound, also known as a substituted styrene, showcases a diverse array of functional groups that play vital roles in its chemical behavior and applications. Here are some fascinating points that highlight the significance of this compound:

  • Structural Complexity: This compound features a vinyl group, a bromo substituent, and a methoxy group, which contribute to its unique reactivity and the possibility of various chemical reactions.
  • Pharmaceutical Applications: Derivatives of styrene compounds are often explored for their potential use in pharmaceuticals, demonstrating properties that may lead to the development of new therapeutic agents.
  • Fluorine’s Influence: The presence of the fluorine atom in the structure can significantly enhance the compound's lipophilicity, influencing how it interacts with biological systems. As a result, compounds like this one are often scrutinized in drug design.
  • Light Absorption: Substituents such as methoxy and fluorine may affect the compound's ability to absorb light, potentially making it useful in photovoltaic applications or as a photosensitizer in photochemical reactions.
  • Research Opportunities: Given its intricate structure, this compound provides ample opportunities for chemical research, particularly in understanding reaction mechanisms involving electrophilic aromatic substitutions and other synthetic processes.

As scientific endeavors continue to explore the vast potential of such compounds, 1-[2-bromo-2-(4-fluorophenyl)-1-phenyl-vinyl]-4-methoxy-benzene stands as a notable example of how small changes in molecular structure can lead to substantial shifts in chemical properties and reactivity.