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1-(2-bromoethyl)-4-chlorobenzene

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Identification
Molecular formula
C8H8BrCl
CAS number
2052-07-5
IUPAC name
1-(2-bromoethyl)-4-chloro-benzene
State
State

At room temperature, 1-(2-bromoethyl)-4-chlorobenzene is typically in a liquid state.

Melting point (Celsius)
-11.00
Melting point (Kelvin)
262.15
Boiling point (Celsius)
239.00
Boiling point (Kelvin)
512.15
General information
Molecular weight
221.50g/mol
Molar mass
221.4900g/mol
Density
1.5050g/cm3
Appearence

1-(2-Bromoethyl)-4-chlorobenzene appears as a clear to a pale yellow liquid. It possesses a mild aromatic odor.

Comment on solubility

Solubility of 1-(2-bromoethyl)-4-chloro-benzene

1-(2-bromoethyl)-4-chloro-benzene, also known as para-chloro-α-bromoethylbenzene, presents interesting solubility characteristics largely influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polarity: This compound features both a halogen (bromo and chloro groups) and an ethyl group, which affects its overall polarity. Compounds with varying polarity can have complex solubility behavior.
  • Solvent Interaction: 1-(2-bromoethyl)-4-chloro-benzene is likely to be soluble in polar organic solvents such as acetone or ethanol, yet may not exhibit high solubility in water. This is indicative of its moderate hydrophobic character.
  • Structure-Activity Relationship: The presence of bulky groups can hinder solubility in smaller polar solvents. This compound’s bromo and chloro substitutions may contribute to a reduced interaction with polar solvents.

In summary, while 1-(2-bromoethyl)-4-chloro-benzene may show reasonable solubility in certain organic solvents, its solubility in water remains limited. This emphasizes the importance of considering molecular structure when predicting solubility behavior.

Interesting facts

Interesting Facts about 1-(2-bromoethyl)-4-chloro-benzene

1-(2-bromoethyl)-4-chloro-benzene is an intriguing compound that features both bromine and chlorine substituents, leading to its useful applications in various chemical processes. Here are some notable insights:

  • Chemical Structure: The compound consists of a benzene ring that is substituted at the para position with a chloro group and at the ortho position with a bromoethyl group. This unique arrangement enhances its reactivity and property profile.
  • Reactivity: The presence of the halogen atoms makes 1-(2-bromoethyl)-4-chloro-benzene quite reactive, which is advantageous in synthetic organic chemistry. It can participate in nucleophilic substitution reactions, yielding useful intermediates for further reactions.
  • Applications: This compound is particularly valuable in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its ability to introduce both a bromo and chloro group into a final product can facilitate complex synthetic pathways.
  • Historic Significance: Compounds with bromine and chlorine have played vital roles in the development of various drugs, demonstrating the importance of halogenated compounds in medicinal chemistry.
  • Safety Considerations: When working with halogenated compounds, it is essential to consider the potential toxicity and environmental impacts. Proper safety protocols should always be observed to minimize risks associated with handling such chemicals.

Overall, 1-(2-bromoethyl)-4-chloro-benzene exemplifies the complexity and versatility of halogenated aromatic compounds. As stated by chemist William H. Perkin, "The interest in organic chemistry is ever-growing, and compounds like this reveal the endless possibilities that arise from simple modifications of structure."

Synonyms
1-(2-BROMOETHYL)-4-CHLOROBENZENE
6529-53-9
4-Chlorophenethyl bromide
Benzene, 1-(2-bromoethyl)-4-chloro-
1-Bromo-2-(4-chlorophenyl)ethane
p-Chlorophenethyl bromide
p-Chloro-.beta.-phenethyl bromide
2-(p-Chlorophenyl)ethyl bromide
DTXSID80215635
p-Chloro-beta-phenethyl bromide
DTXCID10138126
613-774-5
yafmykfauncqpu-uhfffaoysa-n
MFCD00634271
2-(4-chlorophenyl)ethyl bromide
2-(4-chlorophenyl)ethylbromide
SCHEMBL314167
4-CHLOROPHENETHYLBROMIDE
1-(bromoethyl)-4-chlorobenzene
1-(2-Bromethyl)-4-chlorbenzol
4-Chlorophenethyl bromide, 97%
2-(4'-chlorophenyl)ethyl bromide
BCP09513
BBL101257
CL8864
STL555053
1-(2-Bromo-ethyl)-4-chloro-benzene
AKOS011897740
AC-8944
CS-W009513
AS-18477
SY101293
DB-010867
NS00035858
EN300-250166
2-(p-chlorophenyl)ethylbromide;4-chlorophenethyl bromide;