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Memantine

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Identification
Molecular formula
C12H21ClN
CAS number
19982-08-2
IUPAC name
1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine
State
State

At room temperature, Memantine is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
215.78g/mol
Molar mass
215.7760g/mol
Density
1.1260g/cm3
Appearence

Memantine appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine

The solubility of 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine can be understood through various influencing factors. This compound, characterized by its unique structure, generally exhibits limited solubility in water. Below are essential points to consider:

  • Polarity: The presence of the adamantyl group may contribute to lower polarity, affecting its solubility in polar solvents like water.
  • Organic Solvents: However, it is expected to have better solubility in organic solvents such as ethanol, methanol, and dichloromethane due to similar polarities.
  • Hydrophobic Interactions: The bulky structure of the adamantyl moiety may lead to significant hydrophobic effects, reducing compatibility with aqueous environments.
  • Functional Groups: The presence of the amine functional group may allow for some hydrogen bonding, enhancing solubility in certain conditions.

In summary, while 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine shows limited water solubility, it demonstrates a tendency to dissolve in various organic solvents. Its solubility profile is influenced by the interplay of structural features and environmental factors, making it crucial to consider these aspects when working with this compound.

Interesting facts

Interesting Facts about 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine

1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine, often referred to as a synthetic compound, plays a notable role in the field of medicinal chemistry and pharmacology. Here are some fascinating insights into this compound:

  • Psychostimulant Properties: This compound has been studied for its potential stimulant effects, which can be attributed to its unique chemical structure that influences neurotransmitter systems in the brain.
  • Adamantane Framework: Featuring the adamantane structure, this compound showcases the interesting properties associated with cage-like molecular configurations, which can enhance stability and reactivity.
  • Research Implications: The compound's unique properties have sparked interest in its potential therapeutic applications, particularly in treating attention disorders and mood-related conditions.
  • Synthetic Routes: The synthesis of this compound involves complex organic reactions, demonstrating the creativity and precision required in advanced organic chemistry and synthetic methods.
  • Chirality and Isomers: The presence of chiral centers in its structure leads to the possibility of various stereoisomers, which can exhibit different biological activities, making chirality an essential aspect of its study.

The study of 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine reflects the intricate balance between structure and function in pharmacology. As the field evolves, this compound may contribute valuable insights into the development of new therapeutic agents.