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Memantine Hydrochloride

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Identification
Molecular formula
C12H21ClN • HCl
CAS number
41100-52-1
IUPAC name
1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine;hydrochloride
State
State

At room temperature, Memantine Hydrochloride is typically in a solid state.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
306.80
Boiling point (Kelvin)
579.95
General information
Molecular weight
215.76g/mol
Molar mass
215.7620g/mol
Density
1.2655g/cm3
Appearence

Memantine Hydrochloride typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine;hydrochloride

The compound 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine;hydrochloride is an interesting molecule when it comes to solubility characteristics. As a hydrochloride salt, it typically exhibits high solubility in polar solvents

.

Key Points on Solubility:

  • Solvent Interaction: It is expected to be soluble in water due to the presence of the hydrochloride group, which can interact favorably with water molecules via hydrogen bonding.
  • Polarity: The amine group contributes to its overall polarity, further enhancing solubility in polar solvents.
  • Organic Solvents: It may show limited solubility in non-polar organic solvents as the hydrophobic adamantyl group does not favorably interact with these environments.
  • Temperature Effects: Generally, solubility can increase with temperature; thus, heating may enhance the dissolution process in a given solvent.

In summary, the solubility of 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine;hydrochloride is primarily influenced by its ionic nature as a hydrochloride salt, promoting its solubility in polar solvents, while the presence of hydrophobic groups may limit its solubility in less polar media. Understanding these solubility dynamics is essential for applications in both pharmaceuticals and material science.

Interesting facts

Interesting Facts About 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine; hydrochloride

This compound, often referred to in research as a novel psychoactive substance, is an intriguing example of organic chemistry's impact on pharmacology. Here are some key points that highlight its significance:

  • Psychoactive Properties: The compound has garnered attention for its potential stimulant effects, which could have implications in therapeutic settings.
  • Unique Structure: The presence of the adamantyl moiety contributes to its stability and biological activity, showcasing the structural diversity in amine compounds.
  • Chirality: As a compound with chiral centers, it is relevant to discuss its enantiomers. The different configurations can significantly affect the biological activity and efficacy of the compound.
  • Research Interest: As a part of ongoing studies in psychoactive materials, its synthesis and characterization can provide insights into the development of new medications.
  • Regulatory Status: The legal status of such compounds varies greatly across jurisdictions, highlighting the ethical considerations and potential for misuse that accompany these substances.

Overall, 1-(2-chloro-1-adamantyl)-N-methyl-propan-2-amine; hydrochloride serves as a reminder of the complexities of synthetic chemistry, its dual-use potential, and its impact on both science and society.

Synonyms
19835-43-9
ADAMANTANE, 2-CHLORO-1-(2-METHYLAMINOPROPYL)-, HYDROCHLORIDE
2-CHLORO-1-(2-METHYLAMINOPROPYL)ADAMANTANE HYDROCHLORIDE
1-(2-chloro-1-adamantyl)-N-methyl-2-propanamine hydrochloride
1-(2-chloro-1-adamantyl)-N-methylpropan-2-amine;hydrochloride
2-Propylamine, 1-(2-chloro-1-adamantyl)-N-methyl-, hydrochloride
DTXSID30941674
1-(2-Chloroadamantan-1-yl)-N-methylpropan-2-amine--hydrogen chloride (1/1)