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Tamoxifen

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Identification
Molecular formula
C26H29ClO
CAS number
10540-29-1
IUPAC name
1-[2-chloro-1,2-bis(4-methoxyphenyl)vinyl]-3-methoxy-benzene
State
State

At room temperature, Tamoxifen is a solid. It is typically stored in this state for its stability and ease of handling.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
558.30
Boiling point (Kelvin)
831.45
General information
Molecular weight
371.89g/mol
Molar mass
371.8850g/mol
Density
1.1240g/cm3
Appearence

Tamoxifen is generally found as a white crystalline powder. It is practically insoluble in water, but very soluble in methanol, ethanol, and acetone, which gives it a wide range of applications in solution-based processes.

Comment on solubility

Solubility of 1-[2-chloro-1,2-bis(4-methoxyphenyl)vinyl]-3-methoxy-benzene (C26H29ClO)

The solubility of 1-[2-chloro-1,2-bis(4-methoxyphenyl)vinyl]-3-methoxy-benzene in various solvents is influenced by its molecular structure.

In general, the solubility of organic compounds like this one can be assessed based on the following factors:

  • Polarity: This compound contains both polar (e.g., methoxy groups) and non-polar regions, suggesting that it may dissolve well in polar aprotic solvents and certain organic solvents.
  • Occasional solubility: It may exhibit limited solubility in water due to its larger hydrophobic character from the aromatic rings.
  • Solvent choices: Suitable solvents might include:
    • Ether
    • Dichloromethane
    • Acetone

In practical applications, testing solubility in a range of solvents is crucial as it can affect the behavior of the compound in various formulations. As stated in the guiding principle of solubility, "like dissolves like," meaning that this compound's solubility profile is likely to align more closely with non-polar or slightly polar solvents, highlighting the importance of the solvent system chosen for any specific application.

Interesting facts

Interesting Facts about 1-[2-chloro-1,2-bis(4-methoxyphenyl)vinyl]-3-methoxy-benzene

This compound, known for its intricate structure and fascinating properties, belongs to the family of organic compounds that exhibit notable aromatic characteristics. Here are some compelling insights into this compound:

  1. Chemical Structure: The compound features a vinyl group connected to a chlorinated bis-aryl moiety, making it a versatile building block in organic synthesis. The presence of multiple methoxy groups enhances its electron-donating ability, resulting in interesting reactivity patterns.
  2. Applications: This compound is particularly significant in the field of materials science and medicinal chemistry. It may be utilized as a precursor in the synthesis of various polymers and potentially therapeutic compounds. Its structural components resemble those found in certain pharmaceuticals, indicating potential biological activities.
  3. Photophysical Properties: Due to its aromatic nature, this compound may exhibit unique photophysical properties. It could be a candidate for studies in photochemistry, especially in understanding light absorption and emission characteristics which are critical in applications like organic light-emitting diodes (OLEDs).
  4. Reactive Intermediates: Chlorinated organic compounds such as this one are often explored as intermediates in complex chemical reactions, enabling the formation of a diverse range of other valuable compounds. The chlorobenzene moiety may participate in nucleophilic substitution reactions, leading to various derivatives.
  5. Biological Relevance: Compounds with similar structural elements have been studied for their potential anti-cancer properties. The presence of methoxy groups can influence the binding affinity of the compound towards biological targets, making it an exciting area of research.

In summary, 1-[2-chloro-1,2-bis(4-methoxyphenyl)vinyl]-3-methoxy-benzene is not just another organic compound; it is a representation of the interplay between structure and function in chemistry. As researchers continue to explore its properties, we can anticipate that this compound will yield surprising discoveries in various scientific fields.

Synonyms
DivK1c_000818
KBio1_000818
NINDS_000818