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1-(2-Chloroethyl)-3-phenylazetidine

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Identification
Molecular formula
C11H14ClN
CAS number
22083-92-1
IUPAC name
1-(2-chloroethyl)-3-phenyl-azetidine
State
State

In its pure form, the compound is in a liquid state at room temperature, making it suitable for various applications in organic synthesis and chemical reactions.

Melting point (Celsius)
-9.00
Melting point (Kelvin)
264.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
179.69g/mol
Molar mass
179.6550g/mol
Density
1.1106g/cm3
Appearence

The compound is a colorless to pale yellow liquid with a mild aromatic odor. It is usually quite clear, though impurities may give it a slightly different hue.

Comment on solubility

Solubility of 1-(2-chloroethyl)-3-phenyl-azetidine

The solubility of 1-(2-chloroethyl)-3-phenyl-azetidine presents intriguing characteristics due to its structural features. This compound, with its azetidine ring and chloroethyl group, exhibits varied solubility depending on the solvent employed.

In general, solubility can be influenced by several factors:

  • Polarity: Polar solvents, such as water, may not dissolve the nonpolar sections of the molecule effectively.
  • Functional Groups: The presence of the chloro group may enhance solubility in organic solvents.
  • Temperature: Increasing temperature often increases solubility for many compounds.

It is noteworthy that “like dissolves like” applies here; thus, 1-(2-chloroethyl)-3-phenyl-azetidine may find better solubility in organic solvents such as dichloromethane or ethanol rather than polar solvents. Experimental data is essential to determine the precise solubility values in various media, shedding light on its behavior in diverse applications.


Furthermore, understanding the solubility of this compound is crucial for its potential use in pharmaceuticals and agrochemicals, as it affects its bioavailability and overall functionality.

Interesting facts

Interesting Facts about 1-(2-chloroethyl)-3-phenyl-azetidine

1-(2-chloroethyl)-3-phenyl-azetidine is a fascinating compound that presents a variety of intriguing characteristics and applications. As a member of the azetidine family, this compound showcases the unique structural characteristics of four-membered cyclic amines, which distinguishes it in the realm of organic chemistry.

Key Features:

  • Cyclic Structure: The presence of a four-membered ring lends this compound its distinctive chemical properties, enabling it to behave differently compared to larger cyclic compounds.
  • Chloroethyl Group: The 2-chloroethyl substituent introduces reactive properties, making the compound of interest for synthesis reactions and the study of nucleophilic substitution mechanisms.
  • Phenyl Ring: The attached phenyl group adds aromaticity, contributing to the stability and distinct reactivity of the molecule.

This compound has garnered attention in medicinal chemistry due to its potential as a scaffold for drug development. In previous research, compounds with similar structures have demonstrated various biological activities, including:

  • Antitumor properties
  • Antimicrobial effects
  • Neurological activity

Researchers are particularly interested in exploring how small modifications in the structure affect biological activity, thereby paving the way for new therapeutic agents. As one researcher put it, "Understanding the subtle interactions within these cyclic structures can lead to breakthroughs in drug design."

Furthermore, the study of 1-(2-chloroethyl)-3-phenyl-azetidine contributes to our understanding of chemical reactivity and mechanisms, embodying the intersection of theoretical and applied chemistry. With continuing research, this compound's full potential may yet be unlocked, illustrating the ongoing importance of structural diversity in chemical compounds.

Synonyms
1-(2-Chloroethyl)-3-phenylazetidine
7215-12-5
L 2300
AZETIDINE, 1-(2-CHLOROETHYL)-3-PHENYL-
BRN 1426294
DTXSID70222479
DTXCID20144970
5-20-06-00284 (beilstein handbook reference)