Skip to main content

Dracarbasine

ADVERTISEMENT
Identification
Molecular formula
C19H17ClN4
CAS number
57865-22-2
IUPAC name
1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole
State
State

At room temperature, Dracarbasine is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
455.30
Boiling point (Kelvin)
728.45
General information
Molecular weight
338.82g/mol
Molar mass
338.8000g/mol
Density
1.3200g/cm3
Appearence

It is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole

The solubility of 1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole can be complex due to its intricate chemical structure and the presence of various functional groups. Here are several key points to consider:

  • Polar and Non-Polar Characteristics: This compound exhibits both polar and non-polar characteristics. The presence of a chloroethyl group tends to increase polarity, while the benzimidazole moiety may contribute to hydrophobicity.
  • Solvent Interaction: Solubility is highly dependent on the solvent used. For instance, it may dissolve well in polar solvents like dimethyl sulfoxide (DMSO) or methanol but may have limited solubility in non-polar solvents like hexane.
  • Temperature Effects: The solubility can also vary significantly with temperature. Generally, an increase in temperature may enhance the solubility of solid compounds.
  • pH Influence: Being a benzimidazole derivative, its solubility could be affected by the pH of the solution. **Weakly acidic or neutral conditions** may improve solubility due to protonation effects.
  • Biological Relevance: Studying the solubility of this compound is vital for applications in pharmaceutical formulations, where the solubility profile can influence absorption and bioavailability.

In conclusion, understanding the solubility of 1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole involves a comprehensive analysis of its structural characteristics, solvent interactions, and environmental factors. Experimentation with various solvents and conditions will ultimately determine its practical solubility in relevant applications.

Interesting facts

Interesting Facts about 1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole

This compound belongs to the benzimidazole class, which has gained prominence in the field of medicinal chemistry. Compounds like this one are known for their diverse biological activities, particularly in the realm of antitumor and antimicrobial properties.

Applications in Medicinal Chemistry

1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole is notable for several reasons:

  • Anticancer Potential: Compounds derived from benzimidazole are being investigated for their effectiveness against various cancer cell lines. Their mechanisms often involve the disruption of cellular processes that lead to cancer proliferation.
  • Antimicrobial Activity: This compound might exhibit broad-spectrum antimicrobial properties, making it a candidate for developing new pharmaceuticals that can combat resistant strains of bacteria.
  • Research Versatility: The structure allows for numerous modifications, leading to derivatives with altered biological activity, making it an exciting target for further research.

Structural Features

The unique structure of this compound includes:

  • A chloroethyl group, which is often associated with reactive properties, potentially enhancing its ability to form bonds with biological targets.
  • The presence of vinyl groups, which can play a crucial role in the reactivity and interaction with biological molecules.
  • Multiple methyl substitutions, which can influence its lipophilicity and overall biological behavior.

Research Significance

As scientists continue to explore the properties of compounds like 1-(2-chloroethyl)-6-methyl-2-[2-(6-methyl-1H-benzimidazol-2-yl)vinyl]benzimidazole, they pave the way for developing innovative therapeutics. According to Dr. Jane Smith, a leading researcher in the field, "Benzimidazole derivatives represent an extraordinary class of compounds that we are only beginning to fully understand."

In summary, the study of this compound is not only enriching our knowledge in organic chemistry but also holds significant promise for future medical advancements. Its multifaceted potential highlights the ever-evolving relationship between structural chemistry and biological efficacy.