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1-(2-chloroethyl)azepane

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Identification
Molecular formula
C8H16ClN
CAS number
27602-06-2
IUPAC name
1-(2-chloroethyl)azepane
State
State
At room temperature (around 20°C or 68°F), 1-(2-Chloroethyl)azepane is in a liquid state. It is often used in the form of a colorless to light yellow liquid with an amine-like odor.
Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
214.50
Boiling point (Kelvin)
487.65
General information
Molecular weight
161.67g/mol
Molar mass
161.6720g/mol
Density
1.0390g/cm3
Appearence
1-(2-Chloroethyl)azepane is typically a colorless to light yellow liquid with a faint amine-like odor. It is a chemical compound used in various organic synthesis processes.
Comment on solubility

Solubility of 1-(2-chloroethyl)azepane

1-(2-chloroethyl)azepane, with the chemical formula C8H15ClN, exhibits distinct solubility characteristics that can be influenced by several factors. Understanding these characteristics is crucial for various applications in the chemical and pharmaceutical industries.

Solubility Characteristics

  • Polarity: The presence of the chloroethyl group contributes to the compound's polar characteristics, which can enhance its solubility in polar solvents.
  • Solvent Type: 1-(2-chloroethyl)azepane is typically soluble in organic solvents like ethanol and acetone, yet may have limited solubility in water.
  • Temperature Influence: Increased temperature can enhance solubility in organic solvents, aligning with the principle that solubility generally increases with temperature.
  • Concentration Effects: At higher concentrations, the solubility may approach a limit where further dissolution can become difficult, particularly in less compatible solvents.

In summary, while 1-(2-chloroethyl)azepane displays a level of solubility in polar organic solvents, its overall solubility is limited in aqueous environments. Thus, a profound understanding of the solvent interactions and environmental conditions is required when working with this compound.

Interesting facts

Interesting Facts about 1-(2-chloroethyl)azepane

1-(2-chloroethyl)azepane is a fascinating compound with a unique structural framework that invites exploration into its potential applications and properties. This compound belongs to the class of azepanes, which are seven-membered cyclic amines. Here are some intriguing aspects of 1-(2-chloroethyl)azepane:

  • Structural Uniqueness: The presence of a chloroethyl group introduces chlorinated functionality, which can lead to interesting reactivity and interactions with other chemical entities.
  • Potential Pharmaceuticals: Compounds similar to 1-(2-chloroethyl)azepane have been investigated as intermediates in the synthesis of various pharmaceuticals, showcasing the importance of azepane derivatives in medicinal chemistry.
  • Versatile Reactivity: The chloro group can act as an electrophile in nucleophilic substitution reactions, making 1-(2-chloroethyl)azepane a valuable precursor for constructing more complex molecules.
  • Applications in Material Science: The unique structure of azepanes can be harnessed to create polymers or other materials that possess interesting mechanical or chemical properties, expanding the reach of this compound beyond traditional organic chemistry.
  • Significance in Chemical Research: Its synthesis and manipulation have sparked various studies aimed at understanding the nuances of azepane derivatives and their role in organic synthesis.

In conclusion, 1-(2-chloroethyl)azepane is not just another compound; it is a gateway to innovative research opportunities and applications, with the potential to simplify complex chemical reactions and develop novel materials. As stated by renowned chemist Robert H. Grubbs, "Chemistry is the central science," and compounds like 1-(2-chloroethyl)azepane illustrate just how central and versatile chemistry can be in unlocking new technological advancements.

Synonyms
1-(2-chloroethyl)azepane
2205-31-4
1-(2-Chloroethyl)hexahydro-1H-azepine
1-(2-Chloroethyl)hexamethylenimine
1-(2-CHLOROETHYL) HEXAMETHYLENIMINE
1H-AZEPINE, HEXAHYDRO-1-(2-CHLOROETHYL)-
N-(2-Chloroethyl)-hexamethyleneimine
1H-Azepine, 1-(2-chloroethyl)hexahydro-
N-(2-Chloroethyl)hexamethyleneamine
EINECS 218-613-9
BRN 0104112
SCHEMBL224957
DTXSID90176526
CS-M0058
MFCD01665130
AKOS000282517
N-(2-chloroethyl)hexahydro-1h-azepine
CS-14160
DB-308499
NS00027036
EN300-189066
H11734
4-20-00-01407 (Beilstein Handbook Reference)