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Clotrimazole nitrate

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Identification
Molecular formula
C22H17ClN2O4
CAS number
23593-75-1
IUPAC name
1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone;nitrate
State
State

Solid at room temperature.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.00
Boiling point (Celsius)
245.50
Boiling point (Kelvin)
518.65
General information
Molecular weight
344.84g/mol
Molar mass
344.8410g/mol
Density
1.2010g/cm3
Appearence

White or almost white crystalline powder, usually odorless or having a faint characteristic odor.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone nitrate

The solubility of 1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone nitrate is an intriguing aspect of its chemical behavior. This compound exhibits a diverse solubility profile, primarily influenced by its ionic and polar characteristics.

Factors Affecting Solubility

Several factors play a role in determining the solubility of this compound:

  • Polarity: The presence of the imidazolium cation suggests a degree of polarity, which often enhances solubility in polar solvents such as water or methanol.
  • Ionic Interactions: The nitrate anion can interact favorably with polar solvents, possibly leading to higher solubility.
  • Hydrogen Bonding: The compound may engage in hydrogen bonding, notably with solvents that can form hydrogen bonds, increasing its solubility further.

Expected Solubility

While specific solubility values can vary based on conditions, it is often expected that:

  • This compound may be soluble in polar solvents.
  • It may exhibit limited solubility in non-polar solvents due to its ionic nature.

In conclusion, the solubility of 1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone nitrate can be characterized as generally favorable in polar environments, driven by its structural features and ionic characteristics.

Interesting facts

Compound Overview: 1-(2-Chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone Nitrate

The compound 1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone nitrate is an intriguing member of the class of organic compounds known as imidazolium salts, with a structural framework that showcases both aromatic and heterocyclic characteristics.

Interesting Facts:

  • Imidazolium Salts: This compound belongs to a broader group of imidazolium salts, which are often recognized for their enhancements in catalysis and ionic liquid properties. These compounds have applications in various fields, such as material science and electrochemistry.
  • Chlorophenyl Presence: The presence of the 2-chlorophenyl group not only contributes to the compound's unique properties but also may influence its reactivity and interactions with biological targets, making it a point of interest for medicinal chemistry.
  • Potential Biological Activity: There is growing interest in the biological activity of imidazolium salts, particularly their potential as antifungal and antibacterial agents. This specific compound could potentially exhibit interesting pharmacological effects.
  • Formation of Nitrates: The nitrate component in this compound can suggest various reactivity pathways, paving the way for applications in forming energetic materials or as intermediates in synthetic organic chemistry.

As a testament to its versatility, 1-(2-chlorophenyl)-2-(1H-imidazol-1-ium-1-yl)ethanone nitrate exemplifies the intricate interplay between structure and function in chemistry. The fascinating amalgamation of different functional groups highlights the potential for innovation in developing new materials and therapeutic agents. “In chemistry, the properties of a compound can often tell you more about the stories they can create than the sum of their parts.”

Synonyms
ACETOPHENONE, 2'-CHLORO-2-(1-IMIDAZOLYL)-, NITRATE
RefChem:1075901
N-(2-Chlorophenacyl)imidazole nitrate
24155-31-5