Skip to main content

Chlorpheniramine

ADVERTISEMENT
Identification
Molecular formula
C12H10Cl2N2
CAS number
774-23-8
IUPAC name
1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine
State
State

This compound is a solid at room temperature. It is typically stable and not highly volatile in standard conditions.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
256.13g/mol
Molar mass
256.1270g/mol
Density
1.3000g/cm3
Appearence

The compound typically appears as a white to off-white solid. It has a crystalline texture and can vary slightly in color depending on its purity and the presence of impurities.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine

The solubility characteristics of 1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine can vary significantly due to its chemical structure and the presence of chlorine substituents on the phenyl rings. Here are some key points to consider:

  • Polarity: The presence of two chlorine atoms introduces a degree of polarity to the molecule, which can enhance solubility in polar solvents.
  • Solvent Compatibility: 1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine is expected to be more soluble in organic solvents such as methanol, ethanol, and dichloromethane compared to water due to its hydrophobic phenyl groups.
  • Hydrogen Bonding: The presence of the hydrazine functional group (-NH-NH-) may facilitate hydrogen bonding, potentially affecting solubility in certain solvents.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature, making the compound more soluble in hot solvents compared to cold ones.

In conclusion, while 1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine exhibits moderate solubility characteristics, it is generally advised to explore its solubility in different solvents to effectively utilize its properties in various applications.

Interesting facts

Interesting Facts about 1-(2-Chlorophenyl)-2-(3-chlorophenyl)hydrazine

1-(2-Chlorophenyl)-2-(3-chlorophenyl)hydrazine, also known as a substituted hydrazine compound, is noteworthy for its unique structure and properties. Here are some fascinating aspects of this compound:

  • Versatile Derivative: The presence of chlorine atoms in the phenyl rings significantly enhances the compound's reactivity, making it useful in various chemical syntheses.
  • Biological Importance: Compounds like this one have been studied for their potential pharmacological properties, including anticancer and antifungal activities. Some hydrazine derivatives exhibit selective toxicity against certain cancer cells.
  • Synthetic Utility: This compound serves as a building block in the synthesis of other complex organic molecules used in medicinal chemistry and agrochemicals.
  • Reactive Intermediate: Due to its hydrazine functional group, it can act as a nucleophile in several reactions, thus facilitating the formation of new compounds through pathways like hydrazone or azole formation.
  • Research Focus: Ongoing research into hydrazine derivatives like this one is aimed at understanding their mechanisms and optimizing their bioactivity, making them a subject of interest in drug discovery.

In the opinion of many chemists, compounds such as 1-(2-chlorophenyl)-2-(3-chlorophenyl)hydrazine signal the potential for exploring new solutions in medicinal chemistry. As quoted in a recent study, “Understanding the intricate dynamics of such compounds can pave the way for innovations in therapeutic agents.”

As we delve deeper into the chemistry of substances like this, it is crucial to recognize both their practical applications and the challenges associated with their synthesis and use.

Synonyms
SCHEMBL4062316