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Chlorphenamine

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Identification
Molecular formula
C11H15ClNO
CAS number
132-22-9
IUPAC name
1-(2-chlorophenyl)-2-(isopropylamino)ethanol
State
State

At room temperature, the compound is in a solid state, usually distributed in a stable powdered or crystalline form for handling and formulation in various medicinal products.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
201.70g/mol
Molar mass
201.6980g/mol
Density
1.0469g/cm3
Appearence

The compound typically appears as a white crystalline powder. It is often sold in tablet or capsule form when used pharmaceutically. In its raw form, it may exhibit shine or opacity depending on its refinement.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol: C11H15ClNO

The solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol, a compound featuring both aromatic and aliphatic characteristics, can be quite intriguing due to its chemical structure. The presence of a chlorophenyl group and an isopropylamino group significantly influences its interaction with solvents.

Some key points to consider regarding its solubility include:

  • Aromatic Characteristics: The chlorophenyl moiety may enhance solubility in non-polar solvents due to its hydrophobic nature.
  • Polarity of the Amino Group: The isopropylamino substitution introduces polar characteristics, potentially increasing solubility in polar solvents such as water.
  • Hybrid Behavior: The dual nature of this compound suggests it may exhibit variable solubility, depending on the solvent; it could be more soluble in organic solvents over aqueous solutions.

In summary, the solubility of C11H15ClNO is expected to reflect a complex interplay between its polar and non-polar components. This leads to the possibility of different solubility behaviors in various media, making it essential for practical applications to explore experimental solubility assessments under controlled conditions.

Interesting facts

Interesting Facts about 1-(2-Chlorophenyl)-2-(isopropylamino)ethanol

1-(2-Chlorophenyl)-2-(isopropylamino)ethanol, a fascinating compound, is noteworthy for its pharmaceutical significance and unique characteristics. Here are some engaging facts:

  • Pharmacological Potential: This compound exhibits properties that may contribute to its use in various therapeutic areas, particularly in the development of antidepressants and anxiolytics.
  • Synthetic Versatility: The presence of a chlorophenyl group and isopropylamino side chain offers a pathway for chemists to modify and synthesize derivatives, broadening the spectrum of potential biological activities.
  • Mechanism of Action: It is believed that compounds like this interact with the norepinephrine and serotonin systems in the brain, which are crucial for mood regulation.
  • Chemical Stability: Despite its complex structure, the compound exhibits a level of stability that makes it a subject of interest in long-term pharmacological studies.
  • Structure-Activity Relationship (SAR): Understanding how the modification of certain functional groups affects activity can assist chemists in designing more effective medications.

Research surrounding 1-(2-chlorophenyl)-2-(isopropylamino)ethanol is ongoing, with scientists keen to discover more about its effects and potential therapeutic benefits. Such compounds often serve as starting points in the development of new drugs, reminding us of the dynamic and evolving nature of chemical research.

Synonyms
CLORPRENALINE
3811-25-4
Clorprenalina
Clorprenalinum
Isoprophenamin
1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol
Clorprenaline [INN:BAN]
Clorprenalinum [INN-Latin]
Clorprenalina [INN-Spanish]
Isoprophenamine
Clorprenaline-D7
isoprofenamine
EINECS 223-291-8
CLORPRENALINE [MI]
3W4327W76O
CLORPRENALINE [INN]
1-(2-Chlorphenyl)-2-isopropylaminoethanol
1-(o-Chlorophenyl)-2-isopropylaminoethanol
CLORPRENALINE [WHO-DD]
DTXSID3048316
L 20025
1-(2-CHLOROPHENYL)-2-[(PROPAN-2-YL)AMINO]ETHAN-1-OL
Benzenemethanol, 2-chloro-.alpha.-[[(1-methylethyl)amino]methyl]-
Clorprenalinum (INN-Latin)
Clorprenalina (INN-Spanish)
Isoprophenamine (VAN)
o-Chloro-alpha-((isopropylamino)methyl)benzyl alcohol
ORTHO-CHLORO-.ALPHA.((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL
BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)
NCGC00167538-01
Chlorprenaline
1-(2-Chlorophenyl)-2-isopropylaminoethanol
UNII-3W4327W76O
Clorprenaline,(S)
1-(2-Chlorophenyl)-2-(isopropylamino)ethanol
Isoprophenamineisoprofenamine
SCHEMBL250611
CHEMBL1902627
DTXCID5028291
MSK1313
CHEBI:134887
CHEBI:146226
DAA81125
1ST1313D7
AKOS010125624
1ST1313
AB07467
HY-134577
Clorprenaline 100 microg/mL in Acetonitrile
CS-0145577
NS00009158
C90468
1-(2-Chlorophenyl)-2-(isopropylamino)ethanol #
AB01565769_02
EN300-6472709
Clorprenaline, VETRANAL(TM), analytical standard
BRD-A29281099-001-01-0
BRD-A29281099-003-03-2
Q27258116
benzene, 1-chloro-2-(1-hydroxy-2-isopropylamino)ethyl-
o-Chloro-.alpha.-[(isopropylamino)methyl]benzyl alcohol
Z666296432
ORTHO-CHLORO-ALPHA((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL
BENZENEMETHANOL, 2-CHLORO-ALPHA-(((1-METHYLETHYL)AMINO)METHYL)
223-291-8
InChI=1/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H