Skip to main content

Clenbuterol hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C12H18Cl2N2O
CAS number
21898-19-1
IUPAC name
1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride
State
State

Clenbuterol hydrochloride is typically found as a solid at room temperature. It must be stored in a dry environment to prevent it from absorbing moisture and degrading over time.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
313.65g/mol
Molar mass
313.6500g/mol
Density
1.2000g/cm3
Appearence

Clenbuterol hydrochloride typically appears as a white or slightly yellow crystalline powder. This compound is known for its hygroscopic properties, meaning it can readily absorb moisture from the air.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride

The solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride is influenced by various factors, making it an interesting compound to study.

Key Points on Solubility:

  • Hydrophilicity: The presence of the hydrochloride group typically increases the hydrophilicity of the compound, allowing it to dissolve well in polar solvents like water.
  • Hydrate Formation: Being a hydrate implies that the compound can incorporate water molecules into its structure, which can affect its solubility profile.
  • Temperature Effects: Like many organic compounds, its solubility may change with temperature; heating may enhance solubility due to increased molecular motion.

According to solubility principles, compounds that possess basic nitrogen functionalities, such as the isopropylamino group in this compound, often exhibit good solubility in aqueous solutions. This characteristic is particularly relevant in pharmaceutical applications where solubility directly influences bioavailability.

In summary, 1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride is expected to show good solubility in polar solvents, especially water, due to its hydrophilic nature and the effect of hydration.

Interesting facts

Interesting Facts about 1-(2-Chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride

This fascinating compound, often utilized in pharmaceutical chemistry, encapsulates a variety of intriguing aspects worth exploring:

  • Pharmacological Insights: This compound is classified primarily as a pharmaceutical agent, showing potential in the treatment of various ailments due to its unique structural properties.
  • Mechanism of Action: It interacts with certain neurotransmitter systems, particularly those involving serotonin and norepinephrine, thereby influencing mood and cognitive functions. This makes it a candidate for further research into antidepressant and anxiolytic properties.
  • Synthesis Sweet Spot: The synthesis process typically involves reactions that showcase the versatility of organic chemistry. Emerging methods have made it easier to design and modify similar compounds, expanding the frontiers of drug development.
  • Hydrochloride Form: The hydrochloride salt form enhances the compound's stability and solubility, making it more suitable for therapeutic use. This conversion also plays a pivotal role in pharmacokinetics—how the body absorbs and processes the drug.
  • Research Landscape: Ongoing studies are probing into this compound's efficacy and safety profiles, which could potentially lead to new pharmaceutical formulations. Notably, researchers are exploring its potential in treating behavioral disorders, making it an exciting subject for current scientific discussions.
  • Chlorine's Role: The presence of the chlorine atom in the phenyl ring can significantly influence the compound's biological activity. This demonstrates the importance of halogen substitutions in drug design, highlighting the intricate balance of activity and safety in medicinal chemistry.

In conclusion, the study of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrate;hydrochloride is not just an academic exercise; it represents a blend of creativity in synthesis, innovation in pharmacology, and the arduous journey toward better health solutions. As the saying goes in the scientific community, "Every compound has a story to tell."

Synonyms
Asthone
Cosmoline
5588-22-7
Clopinerin
Restanolon
Broncon
Conselt
Kalutein
Pentadoll
Fusca
UNII-T6CRE6WE0W
T6CRE6WE0W
Clorprenaline hydrochloride [USAN:JAN]
clorprenalin hydrochlorid-1-wasser
Isoprophenamine hydrochloride monohydrate
Benzyl alcohol, o-chloro-alpha-((isopropylamino)methyl)-, hydrochloride, monohydrate
Benzenemethanol, 2-chloro-alpha-(((1-methylethyl)amino)methyl)-, hydrochloride, monohydrate
o-Chloro-alpha-((isopropylamino)methyl)benzyl alcohol hydrochloride monohydrate
clorprenaline hydrochloride hydrate
Clorprenaline hydrochloride monohydrate
SCHEMBL45370
CHEMBL3989576
CHEBI:31422
DTXSID80971284
Clorprenaline hydrochloride (JAN/USAN)
CLORPRENALINE HYDROCHLORIDE [USAN]
CLORPRENALINE HYDROCHLORIDE [MART.]
CLORPRENALINE HYDROCHLORIDE [WHO-DD]
D01835
CLORPRENALINE HYDROCHLORIDE MONOHYDRATE [MI]
CLORPRENALINE HYDROCHLORIDE MONOHYDRATE [MART.]
Q27289733
1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol;hydrate;hydrochloride
1-(2-Chlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol--hydrogen chloride--water (1/1/1)
O-Chloro-alpha[(isopropylamino)methyl]benzyl alcohol hydrochloride monohydrate
BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-, HYDROCHLORIDE, MONOHYDRATE