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Clenbuterol Hydrochloride

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Identification
Molecular formula
C12H19Cl2N2O
CAS number
21898-19-1
IUPAC name
1-(2-chlorophenyl)-2-(isopropylamino)ethanol;hydrochloride
State
State

Clenbuterol Hydrochloride is typically available as a solid at room temperature. It is commonly provided as a powder form which is used in chemistry and pharmaceutical applications.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
544.00
Boiling point (Kelvin)
817.15
General information
Molecular weight
277.19g/mol
Molar mass
277.1930g/mol
Density
1.2490g/cm3
Appearence

Clenbuterol Hydrochloride appears as a white or almost white crystalline powder. It is typically odorless and has a slightly bitter taste. The compound is usually distributed as a powder for research and pharmaceutical use.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol hydrochloride

The solubility of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol hydrochloride can vary significantly, primarily influenced by its ionic nature and the characteristics of the solvent. Being a hydrochloride salt, this compound typically has enhanced solubility in polar solvents, especially water. Here are some key points to consider:

  • Polar Solvents: It is generally soluble in water due to the ionization of the hydrochloride group.
  • Non-Polar Solvents: The solubility in non-polar solvents is expected to be low because of the hydrophilic (water-attracting) nature of the amine and hydroxyl groups.
  • Temperature Influence: Increasing temperature may further enhance solubility in solvents like water, as many salts exhibit greater solubility at elevated temperatures.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution; lower pH typically favors its solubility due to the nature of the hydrochloride form.

In summary, the stoichiometric nature of 1-(2-chlorophenyl)-2-(isopropylamino)ethanol hydrochloride results in its preference for polar environments, making it an important consideration in pharmaceutical formulations and various chemical applications. As stated, "the solubility of a compound is one of its most crucial aspects," affecting both its biological activity and its usage in different mediums.

Interesting facts

Interesting Facts about 1-(2-chlorophenyl)-2-(isopropylamino)ethanol; hydrochloride

This compound, commonly known in the pharmaceutical field, has garnered attention due to its unique chemical structure and potential applications. Here are some intriguing aspects to consider:

  • Pharmacological Significance: The compound acts primarily as a serotonin-norepinephrine reuptake inhibitor (SNRI), making it a candidate for antidepressant therapies. This mechanism highlights its importance in managing various mood disorders.
  • Structural Insights: The presence of a 2-chlorophenyl group enhances lipophilicity, potentially influencing its ability to cross biological membranes and interact with neural receptors.
  • Isopropylamino Influence: The isopropylamino functionality can be attributed to its alkaloid characteristics, possibly affecting its activity and stability in the human body.
  • Research Frontiers: Current studies are exploring the compound's efficacy and safety as part of combination therapies, especially in conditions resistant to first-line treatments.
  • Historical Context: Understanding its evolution in pharmaceutical research has led to greater insights concerning similar chemical entities, and how subtle modifications can result in varied therapeutic profiles.

In summary, 1-(2-chlorophenyl)-2-(isopropylamino)ethanol; hydrochloride exemplifies the intricate dance between chemistry and medicine. Its structural nuances not only provide avenues for novel treatment strategies but also underscore the importance of ongoing research in drug development.

Synonyms
clorprenaline hydrochloride
6933-90-0
1-(2-Chlorophenyl)-2-(isopropylamino)ethanol hydrochloride
Clorprenaline HCl
USAF EL-50
Clorprenaline hydrochloride anhydrous
NSC 334693
1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol;hydrochloride
N-Isopropyl-2-hydroxy-2-(o-chlorophenyl)ethylamine hydrochloride
H34A8V28IT
DTXSID5046699
1-(2-chlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol hydrochloride
NSC-334693
DTXCID3026699
Isoprophenamine hydrochloride
CAS-6933-90-0
NCGC00167538-01
EINECS 230-058-4
UNII-H34A8V28IT
MFCD00210837
1-(2-CHLOROPHENYL)-2-(ISOPROPYLAMINO)ETHANOL HCL
(+-)-1-o-Chlorophenyl-2-isopropylaminoethanol hydrochloride
clorprenaline-hydrochloride
Benzenemethanol, 2-chloro-alpha-(((1-methylethyl)amino)methyl)-, hydrochloride
MLS004774039
SCHEMBL406791
CHEMBL2106149
Clorprenaline hydrochloride 100 microg/mL in Acetonitrile
WLN: GR BYQ1MY1&1 &GH
BCP10537
HY-B1347
Tox21_112535
2-Chloro-alpha-((isopropylamino)methyl)benzyl alcohol hydrochloride
NSC334693
s4135
AKOS015963274
Benzyl alcohol, o-chloro-alpha-((isopropylamino)methyl)-, hydrochloride
Clorprenaline HCl - Bio-X trade mark
Tox21_112535_1
CCG-266960
CS-8016
DS-1895
FC64985
CLORPRENALINE HYDROCHLORIDE [JAN]
NCGC00167538-02
AC-28135
BC164327
SMR003500710
ANHYDROUS CLORPRENALINE HYDROCHLORIDE
NS00080596
SW219362-1
SBI-0654003.0001
ANHYDROUS CLORPRENALINE HYDROCHLORIDE [MART.]
Q27279584
1-(2-Chlorophenyl)-2-(isopropylamino)-ethanol hydrochloride
1-(2-chlorophenyl)-2-(isopropylamino)ethan-1-ol hydrochloride
O-CHLORO-.ALPHA.((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL HYDROCHLORIDE
BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-, HYDROCHLORIDE