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Clorotepine

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Identification
Molecular formula
C10H14ClN
CAS number
91393-49-6
IUPAC name
1-(2-chlorophenyl)-2-methyl-propan-2-amine
State
State

At room temperature, Clorotepine is typically found in a liquid state. It has a relatively low freezing point and becomes solid only upon significant cooling.

Melting point (Celsius)
0.00
Melting point (Kelvin)
273.15
Boiling point (Celsius)
259.60
Boiling point (Kelvin)
532.80
General information
Molecular weight
183.67g/mol
Molar mass
183.7530g/mol
Density
0.9105g/cm3
Appearence

Clorotepine is often found as a colorless or light yellow liquid. It may also have a distinct chemical odor typical of amine compounds.

Comment on solubility

Solubility of 1-(2-chlorophenyl)-2-methyl-propan-2-amine

The solubility of 1-(2-chlorophenyl)-2-methyl-propan-2-amine, a secondary amine, can be somewhat intricate due to its unique molecular structure. It exhibits properties that influence how well it dissolves in various solvents:

  • Polar Solvents: This compound tends to be more soluble in polar solvents such as water or alcohols due to its amine functional group, which can form hydrogen bonds.
  • Non-Polar Solvents: Conversely, it may show reduced solubility in non-polar solvents, leading to a preference for environments that can facilitate interactions through dipole moments.
  • Temperature Dependency: Solubility can also be temperature-dependent; generally, an increase in temperature can enhance solubility, especially in polar solvents.

Quote: “Understanding solubility is crucial for the application and effectiveness of chemical compounds in various environments.” This compound's ability to dissolve in specific media plays a vital role in its functionality and utilization in chemical processes.

Overall, while practical solubility data may vary, analyzing the structural characteristics can provide insights for experimental conditions and its behavior in different solutions.

Interesting facts

Interesting Facts about 1-(2-chlorophenyl)-2-methyl-propan-2-amine

1-(2-chlorophenyl)-2-methyl-propan-2-amine, commonly known as a derivative of amphetamine, is a fascinating compound in the world of medicinal chemistry and pharmacology. Its unique structure contributes to various pharmacological activities, making it a subject of interest for both researchers and clinicians.

Pharmacological Significance

This compound is often studied for its potential effects on central nervous system (CNS) stimulation. Here are some key points about its significance:

  • Stimulant Effects: It shares structural similarities with well-known stimulants, suggesting it may enhance energy and alertness.
  • Potential Therapeutic Applications: Research is ongoing to evaluate its effectiveness in treating attention deficit hyperactivity disorder (ADHD) and narcolepsy.
  • Research in Neurotransmission: The compound may influence the release of neurotransmitters such as dopamine and norepinephrine, which are vital in regulating mood and cognition.

Synthesis and Chemical Properties

The synthesis of 1-(2-chlorophenyl)-2-methyl-propan-2-amine typically involves straightforward organic reactions. Important notes include:

  • Chirality: Being a chiral molecule, it exists in various enantiomeric forms, which may exhibit different biological activities.
  • Substituent Influence: The presence of the 2-chlorophenyl group is pivotal in determining the overall pharmacological profile.
  • Structure-Activity Relationship: Understanding how modifications to its structure affect activity can lead to the development of improved therapeutic agents.

Importance in Research

This compound exemplifies the ongoing need for research into amphetamine derivatives as they continue to hold potential for novel treatments in various psychiatric and neurological disorders. Researchers often quote, “Understanding the intricacies of chemical derivatives could unlock new pathways in medicine.”

As an emerging area of study, 1-(2-chlorophenyl)-2-methyl-propan-2-amine may provide insights that bridge chemical properties with real-world applications.

Synonyms
CLORTERMINE
10389-73-8
Clortermina
Clortermine [INN]
1-(2-chlorophenyl)-2-methylpropan-2-amine
Clorterminum
o-Chlorophentermine
1-(o-Chlorophenyl)-2-methyl-2-aminopropane
Clorterminum [INN-Latin]
Clortermina [INN-Spanish]
HSDB 3306
UNII-4FA88HM3IX
4FA88HM3IX
DTXSID0022850
o-Chloro-alpha,alpha-dimethylphenethylamine
1-(o-Chlorophenyl)-2-methyl-2-propylamine
2-Chloro-alpha,alpha-dimethylbenzeneethanamine
CLORTERMINE [MI]
Phenethylamine, o-chloro-alpha,alpha-dimethyl-
CLORTERMINE [HSDB]
Benzeneethanamine, 2-chloro-alpha,alpha-dimethyl-
CLORTERMINE [WHO-DD]
Benzeneethanamine, 2-chloro-.alpha.,.alpha.-dimethyl-
DTXCID302850
1-(2-Chlorophenyl)-2-methyl-2-propanamine
o-Chloro-.alpha.,.alpha.-dimethylphenethylamine
Clorterminum (INN-Latin)
Clortermina (INN-Spanish)
2-CHLORO-ALPHA, ALPHA-DIMETHYLBENZENEETHANAMINE
hxcxasjhzqxckk-uhfffaoysa-n
DEA No. 1647
NSC104068
.alpha.,.alpha.-dimethyl-o-chlorophenethylamine hydrochloride
NCIOpen2_001902
SCHEMBL164137
CHEMBL1697833
CHEBI:134826
Tox21_113863
AB07476
DB01527
NCGC00253747-01
alpha,alpha-dimethyl-2-chlorophenethylamine
2-(2-Chlorophenyl)-1,1-dimethylethylamine
CAS-10389-73-8
NS00067933
1-(2-chlorophenyl)-2-methyl-propan-2-amine
Q5135153
Phenethylamine, o-chloro-.alpha.,.alpha.-dimethyl-, hydrochloride