Skip to main content

Chlorophthalimide

ADVERTISEMENT
Identification
Molecular formula
C10H4ClNO2
CAS number
3391-92-0
IUPAC name
1-(2-chlorophenyl)pyrrole-2,5-dione
State
State

At room temperature, chlorophthalimide is a solid, typically characterized by its stability and firmness. It does not dissolve easily in water, adding to its robustness under standard conditions.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
403.50
Boiling point (Kelvin)
676.65
General information
Molecular weight
207.59g/mol
Molar mass
207.5930g/mol
Density
1.4560g/cm3
Appearence

Chlorophthalimide appears as a white to off-white crystalline powder. Its crystalline nature gives it a distinct texture, and it is primarily opaque with a slight sheen.

Comment on solubility

Solubility of 1-(2-chlorophenyl)pyrrole-2,5-dione

1-(2-chlorophenyl)pyrrole-2,5-dione exhibits interesting solubility characteristics that can be influenced by various factors such as temperature and the presence of different solvents. Here are some key points about its solubility:

  • Solvent Variability: The solubility of this compound can vary significantly between polar and non-polar solvents. It tends to dissolve better in organic solvents.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, making it more soluble at elevated temperatures.
  • Hydrogen Bonding: The presence of functional groups in 1-(2-chlorophenyl)pyrrole-2,5-dione can promote hydrogen bonding with solvents, potentially enhancing its solubility in certain polar solvents.
  • Practical Considerations: When looking to dissolve this compound, it is advisable to consider using solvents such as dimethyl sulfoxide (DMSO) or acetonitrile, which may offer better solubility profiles.

Overall, understanding the solubility of 1-(2-chlorophenyl)pyrrole-2,5-dione is crucial for its applications in chemical synthesis and material science. Always perform solubility tests under controlled conditions to achieve satisfactory results.

Interesting facts

Interesting Facts about 1-(2-chlorophenyl)pyrrole-2,5-dione

1-(2-chlorophenyl)pyrrole-2,5-dione is a fascinating compound that falls within the class of pyrrole derivatives. This compound has sparked interest due to its diverse potential applications in various fields, particularly in medicinal chemistry. Here are some noteworthy points:

  • Medicinal Properties: Compounds containing the pyrrole ring often exhibit interesting biological activities. Pyrrole derivatives have been researched for their potential antibacterial, antifungal, and even anticancer properties. This particular compound may share these characteristics.
  • Chlorine Substitution: The presence of the 2-chlorophenyl group significantly influences the compound's reactivity and biological activity. Chlorine atoms can enhance lipophilicity and modify the binding interactions with biological targets.
  • Structural Versatility: The unique structural framework of pyrrole-2,5-dione allows for various chemical modifications. This enables chemists to synthesize a wide range of derivatives, potentially leading to the discovery of novel therapeutic agents.
  • Applications in Organic Synthesis: Due to its electrophilic nature, 1-(2-chlorophenyl)pyrrole-2,5-dione can serve as a versatile intermediate in organic synthesis, paving the way for the development of more complex molecules.
  • Research Potential: Ongoing research continues to explore the properties and potential applications of this compound. The insights gained from these studies can contribute significantly to expanding the chemical understanding of pyrrole derivatives.

In summary, 1-(2-chlorophenyl)pyrrole-2,5-dione embodies a rich field of exploration for chemists, with its unique structure and potential biological activities. As research unfolds, this compound may prove invaluable in advancing various scientific disciplines.

Synonyms
1203-24-3
1-(2-Chlorophenyl)-1H-pyrrole-2,5-dione
N-(2-Chlorophenyl)maleimide
O-Chphm
o-Chlorophenylmaleimide
N-o-Chlorophenylmaleimide
1H-Pyrrole-2,5-dione, 1-(2-chlorophenyl)-
MALEIMIDE, N-(o-CHLOROPHENYL)-
EINECS 214-869-0
BRN 0145894
AI3-28671
DTXSID40152794
DTXCID0075285
214-869-0
1-(2-chlorophenyl)pyrrole-2,5-dione
N-(2-Chlorophenyl)-maleimide
1-(2-chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione
1-(2-Chloro-phenyl)-pyrrole-2,5-dione
MFCD00022562
n-(o-chlorophenyl)maleimide
CHEMBL565700
Cyto8F7
1H-Pyrrole-2,5-dione, 1-(chlorophenyl)-
1H-Pyrrole-2,5-dione,1-(2-chlorophenyl)-
SCHEMBL58050
1-(2-Chlorophenyl)maleimide
N-(o-chlorophenyl) maleimide
252EC33EVE
KPQOXMCRYWDRSB-UHFFFAOYSA-
ALBB-005200
BDBM50300330
GEO-02892
STK098903
AKOS000116699
LS-01961
PD135223
DB-041548
CS-0307639
NS00023911
EN300-03887
G29547
Z56755406
InChI=1/C10H6ClNO2/c11-7-3-1-2-4-8(7)12-9(13)5-6-10(12)14/h1-6H